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Lambda Interferons: New Cytokines with Old Functions
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scholarly article
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Europe PubMed Central
PMC publication ID
4034011
retrieved
8 September 2017
review article
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Europe PubMed Central
title
Lambda Interferons: New Cytokines with Old Functions
(English)
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Europe PubMed Central
PMC publication ID
4034011
retrieved
8 September 2017
author
Hans Henrik Gad
series ordinal
2
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Europe PubMed Central
PMC publication ID
4034011
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
Rune Hartmann
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4
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Europe PubMed Central
PMC publication ID
4034011
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
author name string
Ole J Hamming
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1
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Europe PubMed Central
PMC publication ID
4034011
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
Søren Paludan
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3
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Europe PubMed Central
PMC publication ID
4034011
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
publication date
25 March 2010
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Europe PubMed Central
PMC publication ID
4034011
retrieved
8 September 2017
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Pharmaceuticals
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Europe PubMed Central
PMC publication ID
4034011
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
volume
3
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Europe PubMed Central
PMC publication ID
4034011
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
issue
4
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Europe PubMed Central
PMC publication ID
4034011
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
page(s)
795-809
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Europe PubMed Central
PMC publication ID
4034011
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retrieved
2 June 2020
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Creative Commons Attribution 4.0 International
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25 March 2010
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cites work
Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines
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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
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Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
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Cytokine-induced depression during IFN-alpha treatment: the role of IL-6 and sleep quality
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Interferon- Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family
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IFN-lambda1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells
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Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity
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The role of genomic data in the discovery, annotation and evolutionary interpretation of the interferon-lambda family
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Human interferon-lambda3 is a potent member of the type III interferon family.
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A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
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Interferon-lambda contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses
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IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity
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IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo
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An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity
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IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes
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Inhibition of type I and type III interferons by a secreted glycoprotein from Yaba-like disease virus.
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Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma
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Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo
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Interferon-lambda-treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells
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Murine interferon lambdas (type III interferons) exhibit potent antiviral activity in vivo in a poxvirus infection model
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Biological activity of interleukins-28 and -29: comparison with type I interferons
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Structural analysis of IL-10 and Type I interferon family members and their complexes with receptor
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Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling
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Cloning of a new type II cytokine receptor activating signal transducer and activator of transcription (STAT)1, STAT2 and STAT3
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IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
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IL-28, IL-29 and their class II cytokine receptor IL-28R
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Crystal structure of recombinant human interleukin-22
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Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
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Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop
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9 September 2017
Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography
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9 September 2017
Other kinases can substitute for Jak2 in signal transduction by interferon-gamma
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9 September 2017
Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma
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Crystal structure of the extracellular region of human tissue factor
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9 September 2017
Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor
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9 September 2017
Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells
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14 September 2017
Regulation of apoptosis by type III interferons.
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Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases
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14 September 2017
Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics
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14 September 2017
Interleukin-29 uses a type 1 interferon-like program to promote antiviral responses in human hepatocytes
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14 September 2017
The potential for recruiting immune responses toward type 1 or type 2 T cell help.
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25 September 2017
Clinical investigation of human alpha interferon in chronic myelogenous leukemia.
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17 June 2018
Three-dimensional crystal structure of recombinant murine interferon-beta
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17 June 2018
Interferon lambda as a potential new therapeutic for hepatitis C.
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21 August 2018
Human interferon lambda-1 (IFN-lambda1/IL-29) modulates the Th1/Th2 response.
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21 August 2018
Viral Infections Activate Types I and III Interferon Genes through a Common Mechanism
1 reference
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Crossref
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https://api.crossref.org/works/10.3390%2FPH3040795
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21 January 2018
Role of deficient type III interferon-λ production in asthma exacerbations
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21 January 2018
Identifiers
DOI
10.3390/PH3040795
1 reference
stated in
Europe PubMed Central
PMC publication ID
4034011
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
PMC publication ID
4034011
1 reference
stated in
Europe PubMed Central
PMC publication ID
4034011
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
PubMed publication ID
27713280
1 reference
stated in
Europe PubMed Central
PMC publication ID
4034011
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713280%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
ResearchGate publication ID
43336629
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