(Q38979760)

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Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12.

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12. (English)

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

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author name string

Rebecca L Dunfee

1

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Elaine R Thomas

2

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Europe PubMed Central

PMC publication ID

8 September 2017

Dana Gabuzda

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

publication date

20 July 2009

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Europe PubMed Central

PMC publication ID

8 September 2017

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

69

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

https://scigraph.springernature.com/pub.10.1186/1742-4690-6-69

0 references

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

1 reference

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9 September 2017

Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals

1 reference

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9 September 2017

Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

1 reference

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9 September 2017

Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.

1 reference

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9 September 2017

Natural resistance of human immunodeficiency virus type 1 to the CD4bs antibody b12 conferred by a glycan and an arginine residue close to the CD4 binding loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

A rapid progressor-specific variant clone of simian immunodeficiency virus replicates efficiently in vivo only in the absence of immune responses

1 reference

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9 September 2017

Structural definition of a conserved neutralization epitope on HIV-1 gp120

1 reference

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9 September 2017

The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.

1 reference

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9 September 2017

GP120: target for neutralizing HIV-1 antibodies

1 reference

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9 September 2017

Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells

1 reference

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9 September 2017

Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome

1 reference

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9 September 2017

Pathogenesis of macrophage tropic HIV-1.

1 reference

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9 September 2017

Correlation of acute humoral response with brain virus burden and survival time in pig-tailed macaques infected with the neurovirulent simian immunodeficiency virus SIVsmmFGb

1 reference

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9 September 2017

The CCR5 and CXCR4 coreceptors--central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Antibody neutralization and escape by HIV-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.

1 reference

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9 September 2017

Cell surface receptors, virus entry and tropism of primate lentiviruses

1 reference

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9 September 2017

Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Identification of shared populations of human immunodeficiency virus type 1 infecting microglia and tissue macrophages outside the central nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Differential CD4/CCR5 utilization, gp120 conformation, and neutralization sensitivity between envelopes from a microglia-adapted human immunodeficiency virus type 1 and its parental isolate

1 reference

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9 September 2017

Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Beyond receptor expression: the influence of receptor conformation, density, and affinity in HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy

1 reference

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9 September 2017

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease

1 reference

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9 September 2017

Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717910

9 September 2017

Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enh

1 reference

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Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion.

1 reference

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9 September 2017

Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementia.

1 reference

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14 September 2017

Preparation and characterization of human HIV type 1 neutralizing reference sera

1 reference

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25 September 2017

The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion.

1 reference

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17 June 2018

HIV-1 tropism for the central nervous system: Brain-derived envelope glycoproteins with lower CD4 dependence and reduced sensitivity to a fusion inhibitor

1 reference

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21 August 2018

Neutralization sensitivity of a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2N) isolated from an infected rhesus macaque with neurological disease

1 reference

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HIV vaccine design and the neutralizing antibody problem

1 reference

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21 August 2018

HIV dementia patients exhibit reduced viral neutralization and increased envelope sequence diversity in blood and brain

1 reference

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21 August 2018

Identifiers

10.1186/1742-4690-6-69

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

ResearchGate publication ID

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