(Q38984903)

8 September 2017

title

Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth (English)

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8 September 2017

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10

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8 June 2020

Stefania Catalano

1

1 reference

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8 June 2020

Daniela Bonofiglio

5

1 reference

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8 June 2020

Marilena Lanzino

6

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8 June 2020

Pietro Rizza

7

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8 June 2020

Ines Barone

12

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8 June 2020

author name string

Cinzia Giordano

2

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8 June 2020

Salvatore Panza

3

1 reference

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8 June 2020

Francesca Chemi

4

1 reference

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8 June 2020

Francesco Romeo

8

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8 June 2020

Suzanne A W Fuqua

9

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8 June 2020

Sebastiano Andò

11

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8 June 2020

language of work or name

English

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publication date

14 June 2014

1 reference

Breast Cancer Research and Treatment

8 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928526%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

146

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8 June 2020

issue

2

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8 June 2020

page(s)

273-285

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What do we know about the mechanisms of aromatase inhibitor resistance?

8 June 2020

cites work

1 reference

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21 January 2018

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Estrogens and PTP1B function in a novel pathway to regulate aromatase enzymatic activity in breast cancer cells.

21 January 2018

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Rapid estradiol/ERalpha signaling enhances aromatase enzymatic activity in breast cancer cells.

21 January 2018

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The direct proliferative stimulus of dehydroepiandrosterone on MCF7 breast cancer cells is potentiated by overexpression of aromatase

21 January 2018

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Autocrine and paracrine actions of breast tumor aromatase. A three-dimensional cell culture study involving aromatase transfected MCF-7 and T-47D cells

21 January 2018

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Mechanisms of estrogen signaling and gene expression via GPR30

21 January 2018

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A transmembrane intracellular estrogen receptor mediates rapid cell signaling

21 January 2018

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Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor, GPR30: a novel signaling pathway with potential significance for breast cancer

21 January 2018

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The ins and outs of GPR30: a transmembrane estrogen receptor

21 January 2018

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Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF

21 January 2018

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Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

21 January 2018

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Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

21 January 2018

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The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells

21 January 2018

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17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30.

21 January 2018

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Measurement of steroid hormone receptors in breast cancer patients on tamoxifen

21 January 2018

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Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305.

21 January 2018

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Estrogen receptor mutations and changes in downstream gene expression and signaling

21 January 2018

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Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity

21 January 2018

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Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway

21 January 2018

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Oncogenic kinase signalling

21 January 2018

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Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation

21 January 2018

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Cross-talk between estrogen receptor and growth factor pathways as a molecular target for overcoming endocrine resistance

21 January 2018

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The role of growth factor receptor pathways in human breast cancer cells adapted to long-term estrogen deprivation

21 January 2018

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Acquired resistance to oestrogen deprivation: role for growth factor signalling kinases/oestrogen receptor cross-talk revealed in new MCF-7X model.

21 January 2018

1 reference

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Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells

21 January 2018

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G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells

21 January 2018

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Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation.

21 January 2018

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Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α

21 January 2018

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Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells

21 January 2018

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Leptin Enhances, via AP-1, Expression of Aromatase in the MCF-7 Cell Line

21 January 2018

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Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells

21 January 2018

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Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells

21 January 2018

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Identification of bioactive constituents of Ziziphus jujube fruit extracts exerting antiproliferative and apoptotic effects in human breast cancer cells.

21 January 2018

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Inhibition of Leydig tumor growth by farnesoid X receptor activation: the in vitro and in vivo basis for a novel therapeutic strategy.

21 January 2018

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A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

21 January 2018

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Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1-mediated p53 activation.

21 January 2018

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Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression

21 January 2018

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Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole

21 January 2018

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DAX-1, as an androgen-target gene, inhibits aromatase expression: a novel mechanism blocking estrogen-dependent breast cancer cell proliferation

21 January 2018

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The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.

21 January 2018

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21 January 2018

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GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells.

21 January 2018

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G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells

21 January 2018

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21 January 2018

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G-protein-coupled receptor 30 and estrogen receptor-alpha are involved in the proliferative effects induced by atrazine in ovarian cancer cells

21 January 2018

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The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line.

21 January 2018

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Elevated Src kinase activity attenuates Tamoxifen response in vitro and is associated with poor prognosis clinically

21 January 2018

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Long-term treatment with tamoxifen facilitates translocation of estrogen receptor alpha out of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells

21 January 2018

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The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

21 January 2018

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Yin-yang activities and vicious cycles in the tumor microenvironment

21 January 2018

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Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3017-4

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3017-4

Mechanisms of endocrine resistance and novel therapeutic strategies in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3017-4

GPR30 as an initiator of tamoxifen resistance in hormone-dependent breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3017-4

10.1007/S10549-014-3017-4

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928526%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 June 2020

1001628092

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928526%20AND%20SRC:MED&resulttype=core&format=json