(Q38987203)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

review article

1 reference

title

Pharmacokinetic properties and drug interactions of apigenin, a natural flavone (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

author name string

Ding Tang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Keli Chen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Luqi Huang

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

language of work or name

English

0 references

publication date

2 November 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Drug Metabolism & Toxicology

26 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

page(s)

323-330

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants

26 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

RP-HPLC analysis of the phenolic compounds of plant extracts. investigation of their antioxidant capacity and antimicrobial activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin and its impact on gastrointestinal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

The Passiflora tripartita (Banana Passion) fruit: a source of bioactive flavonoid C-glycosides isolated by HSCCC and characterized by HPLC–DAD–ESI/MS/MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Isolation and studies of the mutagenic activity in the Ames test of flavonoids naturally occurring in medical herbs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Antidepressant-like effects of apigenin and 2,4,5-trimethoxycinnamic acid from Perilla frutescens in the forced swimming test

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin reverses depression-like behavior induced by chronic corticosterone treatment in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

The effects of apigenin on lipopolysaccharide-induced depressive-like behavior in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Interactions of flavonoids with iron and copper ions: a mechanism for their antioxidant activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

The estrogenic effects of apigenin, phloretin and myricetin based on uterotrophic assay in immature Wistar albino rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin suppresses the expression of VEGF, an important factor for angiogenesis, in endothelial cells via degradation of HIF-1alpha protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Citrus flavonoids luteolin, apigenin, and quercetin inhibit glycogen synthase kinase-3β enzymatic activity by lowering the interaction energy within the binding cavity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin: a promising molecule for cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Selective growth-inhibitory, cell-cycle deregulatory and apoptotic response of apigenin in normal versus human prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

The citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

No evidence for the in vivo activity of aromatase-inhibiting flavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Evaluation of properties of apigenin and [G-3H]apigenin and analytic method development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Enhanced bioavailability of apigenin via preparation of a carbon nanopowder solid dispersion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Preparation of apigenin nanocrystals using supercritical antisolvent process for dissolution and bioavailability enhancement

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Design and evaluation of a self-microemulsifying drug delivery system for apigenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Metabolism of flavonoids via enteric recycling: role of intestinal disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Pharmacokinetics and metabolism of apigenin in female and male rats after a single oral administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Bioavailability of apigenin from apiin-rich parsley in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Intestinal absorption and first-pass metabolism of polyphenol compounds in rat and their transport dynamics in Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Systematic studies of sulfation and glucuronidation of 12 flavonoids in the mouse liver S9 fraction reveal both unique and shared positional preferences

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Metabolism of apigenin by rat liver phase I and phase ii enzymes and by isolated perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Metabolism of apigenin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Metabolism of flavonoids via enteric recycling: mechanistic studies of disposition of apigenin in the Caco-2 cell culture model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Cellular uptake and metabolism of flavonoids and their metabolites: implications for their bioactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

In vitro biotransformation of flavonoids by rat liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Peroxidative metabolism of apigenin and naringenin versus luteolin and quercetin: glutathione oxidation and conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin attenuates insulin-like growth factor-I signaling in an autochthonous mouse prostate cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apoptotic effects of genistein, biochanin-A and apigenin on LNCaP and PC-3 cells by p21 through transcriptional inhibition of polo-like kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: in vitro and in vivo study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Modulation of multidrug resistance protein 1 (MRP1/ABCC1)-mediated multidrug resistance by bivalent apigenin homodimers and their derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin inhibits proliferation of ovarian cancer A2780 cells through Id1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin inhibited migration and invasion of human ovarian cancer A2780 cells through focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Flavones inhibit the proliferation of human tumor cancer cell lines by inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Molecular targets of apigenin in colorectal cancer cells: involvement of p21, NAG-1 and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin induces apoptosis and impairs head and neck carcinomas EGFR/ErbB2 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Enhanced anti-tumor effect of combination therapy with gemcitabine and apigenin in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Interactions between dietary flavonoids apigenin or luteolin and chemotherapeutic drugs to potentiate anti-proliferative effect on human pancreatic cancer cells, in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Synergistic effects of apigenin and paclitaxel on apoptosis of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

5-Fluorouracil combined with apigenin enhances anticancer activity through mitochondrial membrane potential (ΔΨm)-mediated apoptosis in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

5-Fluorouracil combined with apigenin enhances anticancer activity through induction of apoptosis in human breast cancer MDA-MB-453 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin shows synergistic anticancer activity with curcumin by binding at different sites of tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Combination of N-(4-hydroxyphenyl) retinamide and apigenin suppressed starvation-induced autophagy and promoted apoptosis in malignant neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Combination of apigenin treatment with therapeutic HPV DNA vaccination generates enhanced therapeutic antitumor effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Antigenotoxic effect of apigenin against anti-cancerous drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Antigenotoxic effect of apigenin against mitomycin C induced genotoxic damage in mice bone marrow cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Distinction of CYP1A1 and CYP1A2 activity by selective inhibition using fluvoxamine and isosafrole

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin enhances the cytotoxic effects of tumor necrosis factor-related apoptosis-inducing ligand in human rheumatoid arthritis fibroblast-like synoviocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Inhibitory Effect of Apigenin on Pharmacokinetics of Venlafaxine in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

The pharmacokinetics of raloxifene and its interaction with apigenin in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Apigenin inhibits platelet adhesion and thrombus formation and synergizes with aspirin in the suppression of the arachidonic acid pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Dietary flavonoids: bioavailability, metabolic effects, and safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

Biopharmaceutics classification and intestinal absorption study of apigenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17425255.2017.1251903

10.1080/17425255.2017.1251903

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27766890%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference