(Q39000570)

8 September 2017

Extracellular-regulated kinase 2 is activated by the enhancement of hinge flexibility (English)

1 reference

8 September 2017

Kevin M Sours

1

1 reference

8 September 2017

Yao Xiao

series ordinal

2

1 reference

8 September 2017

Natalie G Ahn

series ordinal

3

1 reference

8 September 2017

language of work or name

English

0 references

publication date

15 February 2014

1 reference

Journal of Molecular Biology

8 September 2017

1 reference

8 September 2017

426

1 reference

8 September 2017

9

1 reference

8 September 2017

1925-1935

1 reference

Phosphorylation releases constraints to domain motion in ERK2.

8 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Transitions to catalytically inactive conformations in EGFR kinase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Protein kinases: evolution of dynamic regulatory proteins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Dynamics connect substrate recognition to catalysis in protein kinase A

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38alpha MAP kinase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

A Molecular Brake in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine Kinases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Structural basis for the inhibition of tyrosine kinase activity of ZAP-70

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Release of ADP from the catalytic subunit of protein kinase A: a molecular dynamics simulation study

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Phosphorylation-dependent changes in structure and dynamics in ERK2 detected by SDSL and EPR.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Protein analysis by hydrogen exchange mass spectrometry

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Mechanism of activation of ERK2 by dual phosphorylation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Atomic structure of the MAP kinase ERK2 at 2.3 A resolution

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Distinct patterns of activation-dependent changes in conformational mobility between ERK1 and ERK2.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Hydrogen exchange solvent protection by an ATP analogue reveals conformational changes in ERK2 upon activation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Interdependent domains controlling the enzymatic activity of mitogen-activated protein kinase kinase 1.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001730

Bacterial expression of activated mitogen-activated protein kinases

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24534729

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activity of the MAP kinase ERK2 is controlled by a flexible surface loop

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24534729

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Practical methods for deuterium exchange/mass spectrometry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24534729

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JMB.2014.02.011

1 reference

8 September 2017

1 reference

8 September 2017

PubMed publication ID

24534729

1 reference