(Q39003639)

English

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting α(v)β(3)/α(v)β(5) integrins and IAP proteins.

scientific article published on 16 April 2014

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14 March 2020

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting α(v)β(3)/α(v)β(5) integrins and IAP proteins (English)

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14 March 2020

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14 March 2020

Leonardo Manzoni

2

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14 March 2020

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14 March 2020

Alberto Dal Corso

4

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14 March 2020

Mattia Manzotti

5

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14 March 2020

Lorenzo Pignataro

7

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14 March 2020

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14 March 2020

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14 March 2020

Pierfausto Seneci

11

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14 March 2020

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M Mingozzi

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14 March 2020

F Innamorati

6

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14 March 2020

D Delia

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14 March 2020

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16 April 2014

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14 March 2020

Organic and Biomolecular Chemistry

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14 March 2020

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14 March 2020

20

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14 March 2020

3288-3302

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14 March 2020

Resistance to beta-lactam antibiotics

1 reference

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Ligand binding to integrins

1 reference

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21 January 2018

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21 January 2018

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21 January 2018

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1 reference

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21 January 2018

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

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21 January 2018

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

1 reference

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21 January 2018

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

1 reference

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21 January 2018

A NMR and computational study of Smac mimics targeting both the BIR2 and BIR3 domains in XIAP protein.

1 reference

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21 January 2018

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

1 reference

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21 January 2018

Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy.

1 reference

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21 January 2018

Rational design, synthesis and characterization of potent, drug-like monomeric Smac mimetics as pro-apoptotic anticancer agents

1 reference

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21 January 2018

Integrin targeted delivery of chemotherapeutics

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21 January 2018

Design, synthesis, and biological evaluation of novel cRGD-paclitaxel conjugates for integrin-assisted drug delivery.

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21 January 2018

Synthesis and biological evaluation (in vitro and in vivo) of cyclic arginine-glycine-aspartate (RGD) peptidomimetic-paclitaxel conjugates targeting integrin αVβ3.

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21 January 2018

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21 January 2018

Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization.

1 reference

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21 January 2018

Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization

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21 January 2018

Rapid chromatographic technique for preparative separations with moderate resolution

1 reference

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21 January 2018

Cyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands

1 reference

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21 January 2018

Identifiers

10.1039/C4OB00207E

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24737345%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24737345%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

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