(Q39005466)

English

Functional and physical competition between phospholamban and its mutants provides insight into the molecular mechanism of gene therapy for heart failure.

scientific article published on 12 April 2011

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Functional and physical competition between phospholamban and its mutants provides insight into the molecular mechanism of gene therapy for heart failure (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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Razvan L Cornea

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Christine B Karim

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Elizabeth L Lockamy

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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publication date

12 April 2011

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Biochemical and Biophysical Research Communications

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

408

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

388-392

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Heart disease and stroke statistics--2011 update: a report from the American Heart Association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Phospholamban: a crucial regulator of cardiac contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Targeting phospholamban by gene transfer in human heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Role of cysteine residues in structural stability and function of a transmembrane helix bundle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Phospholamban: protein structure, mechanism of action, and role in cardiac function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Three-dimensional crystals of CaATPase from sarcoplasmic reticulum. Symmetry and molecular packing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Lipid-mediated folding/unfolding of phospholamban as a regulatory mechanism for the sarcoplasmic reticulum Ca2+-ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Phosphorylation-dependent conformational switch in spin-labeled phospholamban bound to SERCA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

Direct detection of phospholamban and sarcoplasmic reticulum Ca-ATPase interaction in membranes using fluorescence resonance energy transfer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

9 September 2017

A recombinant antibody increases cardiac contractility by mimicking phospholamban phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

14 September 2017

Fluorescence energy transfer between Ca2+transport ATPase molecules in artificial membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

14 September 2017

Phospholamban inhibitory function is activated by depolymerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

25 September 2017

The transgenic expression of highly inhibitory monomeric forms of phospholamban in mouse heart impairs cardiac contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

17 June 2018

Co-reconstitution of phospholamban mutants with the Ca-ATPase reveals dependence of inhibitory function on phospholamban structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

17 June 2018

Comparative studies of cardiac and skeletal sarcoplasmic reticulum ATPases. Effect of a phospholamban antibody on enzyme activation by Ca2+.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

17 June 2018

Amino acids Glu2 to Ile18 in the cytoplasmic domain of phospholamban are essential for functional association with the Ca(2+)-ATPase of sarcoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

17 June 2018

Controlling the inhibition of the sarcoplasmic Ca2+-ATPase by tuning phospholamban structural dynamics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

21 August 2018

Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

21 August 2018

Role of leucine 31 of phospholamban in structural and functional interactions with the Ca2+ pump of cardiac sarcoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

21 August 2018

Conformational changes within the cytosolic portion of phospholamban upon release of Ca-ATPase inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

21 August 2018

Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3212041

21 August 2018

Calcium and heart failure: the cycle game

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nature and site of phospholamban regulation of the Ca2+ pump of sarcoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations of Sarcoplasmic Reticulum Proteins in Failing Human Dilated Cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A leucine zipper stabilizes the pentameric membrane domain of phospholamban and forms a coiled-coil pore structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purified, reconstituted cardiac Ca2+-ATPase is regulated by phospholamban but not by direct phosphorylation with Ca2+/calmodulin-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Ser16 phosphorylation on the allosteric transitions of phospholamban/Ca(2+)-ATPase complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of reversal of phospholamban inhibition of the cardiac Ca2+-ATPase by protein kinase A and by anti-phospholamban monoclonal antibody 2D12

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reexamination of the role of the leucine/isoleucine zipper residues of phospholamban in inhibition of the Ca2+ pump of cardiac sarcoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gender influences on sarcoplasmic reticulum Ca2+-handling in failing human myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defining the molecular components of calcium transport regulation in a reconstituted membrane system

1 reference

https://pubmed.ncbi.nlm.nih.gov/21510919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBRC.2011.04.023

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21510919%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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