(Q39007706)

English

Immunization with an engineered mutant trans-sialidase highly protects mice from experimental Trypanosoma cruzi infection: a vaccine candidate

scientific article published on 18 March 2008

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 September 2017

Immunization with an engineered mutant trans-sialidase highly protects mice from experimental Trypanosoma cruzi infection: a vaccine candidate (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Trypanosoma cruzi

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author name string

Germán H Fontanella

1

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Kristof De Vusser

2

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Wouter Laroy

3

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Lucas Daurelio

4

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Ana Lía Nocito

5

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Silvia Revelli

6

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Europe PubMed Central

PubMed publication ID

8 September 2017

Roland Contreras

7

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Europe PubMed Central

PubMed publication ID

8 September 2017

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publication date

18 March 2008

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Europe PubMed Central

PubMed publication ID

8 September 2017

number of pages

13

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Europe PubMed Central

PubMed publication ID

8 September 2017

26

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Europe PubMed Central

PubMed publication ID

8 September 2017

19

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Europe PubMed Central

PubMed publication ID

8 September 2017

2322-2334

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Europe PubMed Central

PubMed publication ID

8 September 2017

Generation, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Structural and functional properties of Trypanosoma trans-sialidase

1 reference

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7 January 2021

Thymocyte depletion in Trypanosoma cruzi infection is mediated by trans-sialidase-induced apoptosis on nurse cells complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Differential expression of a virulence factor, the trans-sialidase, by the main Trypanosoma cruzi phylogenetic lineages

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Treatment of chronic Chagas' disease with benznidazole: clinical and serologic evolution of patients with long-term follow-up

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Immunization with a plasmid DNA containing the gene of trans-sialidase reduces Trypanosoma cruzi infection in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Comparison of antibody and protective immune responses against Trypanosoma cruzi infection elicited by immunization with a parasite antigen delivered as naked DNA or recombinant protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

DNA sequences encoding CD4+ and CD8+ T-cell epitopes are important for efficient protective immunity induced by DNA vaccination with a Trypanosoma cruzi gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Coadministration of an interleukin-12 gene and a Trypanosoma cruzi gene improves vaccine efficacy

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

A DNA-priming protein-boosting regimen significantly improves type 1 immune response but not protective immunity to Trypanosoma cruzi infection in a highly susceptible mouse strain

2 references

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

based on heuristic

inferred from DOI database lookup

Protective Immunity Against Trypanosoma cruzi Infection in a Highly Susceptible Mouse Strain After Vaccination with Genes Encoding the Amastigote Surface Protein-2 and Trans-Sialidase

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Immune responses against a single CD8+-T-cell epitope induced by virus vector vaccination can successfully control Trypanosoma cruzi infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Adjuvant effect of the Propionibacterium acnes and its purified soluble polysaccharide on the immunization with plasmidial DNA containing a Trypanosoma cruzi gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Control of Trypanosoma cruzi infection and changes in T-cell populations induced by a therapeutic DNA vaccine in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Long-term protective immunity induced against Trypanosoma cruzi infection after vaccination with recombinant adenoviruses encoding amastigote surface protein-2 and trans-sialidase

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Immune system pathogenesis is prevented by the neutralization of the systemic trans-sialidase from Trypanosoma cruzi during severe infections

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Preclinical and clinical safety studies on DNA vaccines

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Carbohydrates in transplantation

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Mannose receptor-mediated regulation of serum glycoprotein homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-alpha-D-mannosidase for N-glycan engineering in Pichia pastoris

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Heterologous protein expression in the methylotrophic yeast Pichia pastoris

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Production of human compatible high mannose-type (Man5GlcNAc2) sugar chains in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

In vivo synthesis of mammalian-like, hybrid-type N-glycans in Pichia pastoris

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Glycan-regulated antigen processing of a protein in the endoplasmic reticulum can uncover cryptic cytotoxic T cell epitopes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Cloning of Trypanosoma cruzi trans-sialidase and expression in Pichia pastoris.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Ultrasensitive profiling and sequencing of N-linked oligosaccharides using standard DNA-sequencing equipment.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Differential susceptibility to acute Trypanosoma cruzi infection in BALB/c and C57BL/6 mice is not associated with a distinct parasite load but cytokine abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Humoral and cellular immune responses in BALB/c and C57BL/6 mice immunized with cytoplasmic (CRA) and flagellar (FRA) recombinant repetitive antigens, in acute experimental Trypanosoma cruzi infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

TNF-alpha is expressed at sites of parasite and tissue destruction in the spleen of mice acutely infected with Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

New technologies for making vaccines

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Trypanosome trans-sialidase targets TrkA tyrosine kinase receptor and induces receptor internalization and activation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

A sexual dimorphism in intrathymic sialylation survey is revealed by the trans-sialidase from Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Acute Trypanosoma cruzi infection is associated with anemia, thrombocytopenia, leukopenia, and bone marrow hypoplasia: reversal by nifurtimox treatment

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Innate and acquired immunity in the pathogenesis of Chagas disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Adjuvants designed for veterinary and human vaccines

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

The mannose receptor: linking homeostasis and immunity through sugar recognition

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Trypanosoma cruzi trans-sialidase potentiates T cell activation through antigen-presenting cells: role of IL-6 and Bruton's tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

CD8+ T-Cell responses to Trypanosoma cruzi are highly focused on strain-variant trans-sialidase epitopes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

Trans-sialidase: a unique enzyme activity discovered in the protozoan Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2008.02.060

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.VACCINE.2008.02.060

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

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