(Q39019207)

8 September 2017

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title

Circadian time signatures of fitness and disease (English)

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8 September 2017

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Joseph Bass

1

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8 September 2017

Mitchell A Lazar

series ordinal

2

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8 September 2017

language of work or name

English

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publication date

1 November 2016

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8 September 2017

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8 September 2017

volume

354

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8 September 2017

issue

6315

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8 September 2017

page(s)

994-999

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Clock Mutants of Drosophila melanogaster

8 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Molecular architecture of the mammalian circadian clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Mammalian Per-Arnt-Sim proteins in environmental adaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

A role for casein kinase 2 in the mechanism underlying circadian temperature compensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian Oscillators: Around the Transcription-Translation Feedback Loop and on to Output

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Genetic basis of human circadian rhythm disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

A serum shock induces circadian gene expression in mammalian tissue culture cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Chromatin Scanning by Dynamic Binding of Pioneer Factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Coordinated transcription of key pathways in the mouse by the circadian clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Extensive and divergent circadian gene expression in liver and heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Transcriptional architecture and chromatin landscape of the core circadian clock in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

The initiation of liver development is dependent on Foxa transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

GENE REGULATION. Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

SIRT1 regulates circadian clock gene expression through PER2 deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian orchestration of the hepatic proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Peroxiredoxins are conserved markers of circadian rhythms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian Oscillation of Sulfiredoxin in the Mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Melanopsin: An opsin in melanophores, brain, and eye

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

The CRTC1-SIK1 pathway regulates entrainment of the circadian clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian rhythm of redox state regulates excitability in suprachiasmatic nucleus neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Hypothalamic regulation of sleep and circadian rhythms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Obesity and metabolic syndrome in circadian Clock mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Sleep and circadian rhythms: key components in the regulation of energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

The transcriptional repressor DEC2 regulates sleep length in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Intercellular coupling confers robustness against mutations in the SCN circadian clock network

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Entrainment of the circadian clock in the liver by feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

High-fat diet disrupts behavioral and molecular circadian rhythms in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Reprogramming of the circadian clock by nutritional challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Resetting of circadian time in peripheral tissues by glucocorticoid signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Temperature as a universal resetting cue for mammalian circadian oscillators

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein gene Cirbp

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Blood-borne circadian signal stimulates daily oscillations in actin dynamics and SRF activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

The circadian molecular clock creates epidermal stem cell heterogeneity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Resonating circadian clocks enhance fitness in cyanobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Impact of circadian misalignment on energy metabolism during simulated nightshift work

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian timing of food intake contributes to weight gain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Meal timing and composition influence ghrelin levels, appetite scores and weight loss maintenance in overweight and obese adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Social jetlag and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Rotating night shifts and risk of breast cancer in women participating in the nurses' health study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Age-related decline in circadian output

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Peripheral Circadian Clocks Mediate Dietary Restriction-Dependent Changes in Lifespan and Fat Metabolism in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Loss of cryptochrome reduces cancer risk in p53 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Control of skin cancer by the circadian rhythm

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Identification of Circadian Determinants of Cancer Chronotherapy through In Vitro Chronopharmacology and Mathematical Modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Roles of circadian rhythmicity and sleep in human glucose regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Circadian variation of blood pressure and the vascular response to asynchronous stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

Small molecule modifiers of circadian clocks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAH4965

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAH4965

1 reference

8 September 2017

1 reference