(Q39025319)

English

CD134-allodepletion allows selective elimination of alloreactive human T cells without loss of virus-specific and leukemia-specific effectors

scientific article published on May 2008

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Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

CD134-allodepletion allows selective elimination of alloreactive human T cells without loss of virus-specific and leukemia-specific effectors (English)

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

1 reference

based on heuristic

inferred from title

author name string

Xupeng Ge

1

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Julia Brown

2

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Megan Sykes

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Vassiliki A Boussiotis

4

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

publication date

1 May 2008

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Biology of Blood and Marrow Transplantation

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

14

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

518-530

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Reconstitution of FOXP3+ regulatory T cells (Tregs) after CD25-depleted allotransplantation in elderly patients and association with acute graft-versus-host disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Roles of OX40 in the pathogenesis and the control of diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

TNF/TNFR family members in costimulation of T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Costimulation by CD137/4-1BB inhibits T cell apoptosis and induces Bcl-xL and c-FLIP(short) via phosphatidylinositol 3-kinase and AKT/protein kinase B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

The costimulation-regulated duration of PKB activation controls T cell longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Allogeneic hematopoietic transplantation as adoptive immunotherapy. Induction of graft-versus-malignancy as primary therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Reinventing bone marrow transplantation: reducing toxicity using nonmyeloablative, preparative regimens and induction of graft-versus-malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

Differential cellular immune responsiveness to systems of the major histocompatibility complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

9 September 2017

T-cell responses directed against multiple HLA-A*0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

14 September 2017

Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

14 September 2017

Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

14 September 2017

Selective depletion of major and minor histocompatibility antigen reactive T cells: towards prevention of acute graft-versus-host disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

25 September 2017

Depletion of alloreactive T cells by a specific anti-interleukin-2 receptor p55 chain immunotoxin does not impair in vitro antileukemia and antiviral activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

25 September 2017

Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

17 June 2018

Elimination of graft-versus-host disease by in-vitro depletion of alloreactive lymphocytes with a monoclonal rat anti-human lymphocyte antibody (CAMPATH-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

17 June 2018

Bone marrow transplantation for chronic myelogenous leukemia in chronic phase. Increased risk for relapse associated with T-cell depletion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

17 June 2018

Specific elimination of alloreactive T cells by an anti-interleukin-2 receptor B chain-specific immunotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

17 June 2018

Enhanced CD4 T cell responsiveness in the absence of 4-1BB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

21 August 2018

Triggering of OX40 (CD134) on CD4(+)CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

21 August 2018

4-1BB-mediated immunotherapy of rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

21 August 2018

A signal through OX40 (CD134) allows anergic, autoreactive T cells to acquire effector cell functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

21 August 2018

Early host CD8 T-cell recovery and sensitized anti-donor interleukin-2-producing and cytotoxic T-cell responses associated with marrow graft rejection following nonmyeloablative allogeneic bone marrow transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

21 August 2018

Immune responses in 4-1BB (CD137)-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

21 August 2018

The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

21 August 2018

Specific depletion of alloreactivity against haplotype mismatched related individuals by a recombinant immunotoxin: a new approach to graft-versus-host disease prophylaxis in haploidentical bone marrow transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

21 August 2018

Functional study of residual T lymphocytes after specific elimination of alloreactive T cells by a specific anti-interleukin-2 receptor Bk chain immunotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

21 August 2018

Transplantation of anergic histoincompatible bone marrow allografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

4 November 2018

Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: a method to ameliorate graft-versus-host disease and extend the donor pool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

4 November 2018

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423190

4 November 2018

Optimized clinical-scale culture conditions for ex vivo selective depletion of host-reactive donor lymphocytes: a strategy for GvHD prophylaxis in allogeneic PBSC transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD137‐Mediated T Cell Co‐Stimulation Terminates Existing Autoimmune Disease in SLE‐Prone NZB/NZW F1 Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of CD134 (OX40)-CD134L interaction ameliorates lethal acute graft-versus-host disease in a murine model of allogeneic bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of peripheral blood OX40+(CD134+) T cells with chronic graft-versus-host disease in patients who underwent allogeneic hematopoietic stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alloantigen-specific T-cell depletion in a major histocompatibility complex fully mismatched murine model provides effective graft-versus-host disease prophylaxis in the presence of lymphoid engraftment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune reconstitution without graft-versus-host disease after haemopoietic stem-cell transplantation: a phase 1/2 study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transplantation for acute leukaemia with HLA-A and B nonidentical parental marrow cells fractionated with soybean agglutinin and sheep red blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of anti-T-cell globulin on GVHD in leukemic patients treated with BMT

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of anti-T-cell monoclonal antibody OKT3 to prevent acute graft-versus-host disease in allogeneic bone-marrow transplantation for acute leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pretreatment of donor bone marrow with monoclonal antibody OKT3 for prevention of acute graft-versus-host disease in allogeneic histocompatible bone-marrow transplantation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Graft-versus-host disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of in vitro T cell clonal anergy by IL-2 stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequency of anti-recipient alloreactive helper T-cell precursors in donor blood and graft-versus-host disease after HLA-identical sibling bone-marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early reactivation of cytomegalovirus and high risk of interstitial pneumonitis following T-depleted BMT for adults with hematological malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the T-cell activation antigen, OX-40, identifies alloreactive T cells in acute graft-versus-host disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of graft-versus-host disease (GVHD) by elimination of recipient-reactive donor T cells with recombinant toxins that target the interleukin 2 (IL-2) receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional assessment and specific depletion of alloreactive human T cells using flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

OX40 (CD134) engagement drives differentiation of CD4+ T cells to effector cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation-associated phenotype of CD3 T cells in acute graft-versus-host disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-OX40 stimulation in vivo enhances CD8+ memory T cell survival and significantly increases recall responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of OX40 ligand+ mast cells in chronic GVHD after allogeneic hematopoietic stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410894

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBMT.2008.02.010

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

ResearchGate publication ID

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