(Q39035790)

8 September 2017

The involvement of NADPH oxidase-mediated ROS in cytokine secretion from macrophages induced by Mycobacterium tuberculosis ESAT-6. (English)

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Mycobacterium tuberculosis

8 September 2017

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author name string

Weiwei Liu

1

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8 September 2017

Yuan Peng

2

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8 September 2017

Yanlin Yin

3

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8 September 2017

Zhihui Zhou

4

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8 September 2017

Wanding Zhou

5

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8 September 2017

Yalei Dai

6

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8 September 2017

1 June 2014

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8 September 2017

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8 September 2017

37

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8 September 2017

3

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8 September 2017

880-892

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https://scigraph.springernature.com/pub.10.1007/s10753-013-9808-7

8 September 2017

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Toll-like receptor 9 is required for full host resistance to Mycobacterium avium infection but plays no role in induction of Th1 responses

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Pharmacological analysis of signal transduction pathways required for mycobacterium tuberculosis-induced IL-8 and MCP-1 production in human peripheral monocytes

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Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications

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The ESAT6 protein of Mycobacterium tuberculosis induces apoptosis of macrophages by activating caspase expression

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The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

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Mycobacterium tuberculosis H37Rv ESAT-6-CFP-10 complex formation confers thermodynamic and biochemical stability

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Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence

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Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages

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Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

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Role of mitogen-activated protein kinase pathways in the production of tumor necrosis factor-alpha, interleukin-10, and monocyte chemotactic protein-1 by Mycobacterium tuberculosis H37Rv-infected human monocytes.

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Macrophage signalling upon mycobacterial infection: the MAP kinases lead the way.

21 January 2018

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ESAT-6 induced COX-2 expression involves coordinated interplay between PI3K and MAPK signaling.

21 January 2018

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Mycobacterium tuberculosis 6-kDa early secreted antigenic target (ESAT-6) protein downregulates lipopolysaccharide induced c-myc expression by modulating the extracellular signal regulated kinases 1/2

21 January 2018

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21 January 2018

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Oxidative stress augments the production of matrix metalloproteinase-1, cyclooxygenase-2, and prostaglandin E2 through enhancement of NF-kappa B activity in lipopolysaccharide-activated human primary monocytes

21 January 2018

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Regulation of innate immunity by NADPH oxidase

21 January 2018

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Selective targeting of NADPH oxidase for cardiovascular protection

21 January 2018

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ESAT-6 proteins: protective antigens and virulence factors?

21 January 2018

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Control of mycobacterial replication in human macrophages: roles of extracellular signal-regulated kinases 1 and 2 and p38 mitogen-activated protein kinase pathways

21 January 2018

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Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and -3 expression and secretion via NF-kappaB- and Activator Protein-1-dependent monocyte networks

21 January 2018

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Continuous treatment with recombinant Mycobacterium tuberculosis CFP-10-ESAT-6 protein activated human monocyte while deactivated LPS-stimulated macrophage

21 January 2018

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ASK1-p38 MAPK-p47phox activation is essential for inflammatory responses during tuberculosis via TLR2-ROS signalling

21 January 2018

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Cellular response to oxidative stress: signaling for suicide and survival

21 January 2018

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Oxidants and signaling by mitogen-activated protein kinases in lung epithelium

21 January 2018

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Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases

21 January 2018

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NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expression

21 January 2018

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CCL2 responses to Mycobacterium tuberculosis are associated with disease severity in tuberculosis

21 January 2018

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12 December 2020

Early secreted antigen ESAT-6 of Mycobacterium tuberculosis promotes protective T helper 17 cell responses in a toll-like receptor-2-dependent manner

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12 December 2020

Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts

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12 December 2020

Reactive oxygen species in cell signaling

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12 December 2020

Redox homeostasis in mycobacteria: the key to tuberculosis control?

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12 December 2020

Effects of Mycobacterium tuberculosis ESAT-6/CFP-10 fusion protein on the autophagy function of mouse macrophages

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12 December 2020

T helper 1 and T helper 2 cells respond differentially to chemokines

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12 December 2020

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

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12 December 2020

Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages

1 reference

12 December 2020

10.1007/S10753-013-9808-7

Identifiers

DOI

1 reference

8 September 2017

1 reference