(Q39051119)

8 September 2017

The control of DNA repair by the cell cycle (English)

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8 September 2017

2

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8 September 2017

Nicole Hustedt

1

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8 September 2017

1 December 2016

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8 September 2017

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8 September 2017

19

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8 September 2017

1

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8 September 2017

1-9

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https://scigraph.springernature.com/pub.10.1038/ncb3452

8 September 2017

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cites work

The DNA-damage response in human biology and disease

1 reference

Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

21 January 2018

1 reference

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

21 January 2018

1 reference

Is non-homologous end-joining really an inherently error-prone process?

21 January 2018

1 reference

Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks

21 January 2018

1 reference

Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination

21 January 2018

1 reference

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

21 January 2018

1 reference

Noncanonical views of homology-directed DNA repair

21 January 2018

1 reference

Analysis of mouse Rad54 expression and its implications for homologous recombination.

21 January 2018

1 reference

Human CtIP promotes DNA end resection

21 January 2018

1 reference

Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks

21 January 2018

1 reference

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

21 January 2018

1 reference

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

21 January 2018

1 reference

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

21 January 2018

1 reference

BRCA1 and BRCA2: different roles in a common pathway of genome protection

21 January 2018

1 reference

Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1-Top3.

21 January 2018

1 reference

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

21 January 2018

1 reference

Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast

21 January 2018

1 reference

Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells

21 January 2018

1 reference

Interplay between Ku and Replication Protein A in the Restriction of Exo1-mediated DNA Break End Resection

21 January 2018

1 reference

Double-strand break end resection and repair pathway choice

21 January 2018

1 reference

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

21 January 2018

1 reference

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

21 January 2018

1 reference

Characterization of homologous recombination induced by replication inhibition in mammalian cells

21 January 2018

1 reference

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

21 January 2018

1 reference

The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle

21 January 2018

1 reference

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

21 January 2018

1 reference

CDK targets Sae2 to control DNA-end resection and homologous recombination

21 January 2018

1 reference

Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection

21 January 2018

1 reference

Functional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break.

21 January 2018

1 reference

Human CtIP mediates cell cycle control of DNA end resection and double strand break repair

21 January 2018

1 reference

CtIP: A DNA damage response protein at the intersection of DNA metabolism

21 January 2018

1 reference

The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair

21 January 2018

1 reference

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

21 January 2018

1 reference

DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains

21 January 2018

1 reference

Genetic steps of mammalian homologous repair with distinct mutagenic consequences

21 January 2018

1 reference

BRCA1 promotes induction of ssDNA by ionizing radiation

21 January 2018

1 reference

BRCA1 accelerates CtIP-mediated DNA-end resection

21 January 2018

1 reference

Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection

21 January 2018

1 reference

A mechanism for the suppression of homologous recombination in G1 cells

21 January 2018

1 reference

Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.

21 January 2018

1 reference

Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice

21 January 2018

1 reference

Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells

21 January 2018

1 reference

CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination

21 January 2018

1 reference

Controlling DNA-end resection: a new task for CDKs

21 January 2018

1 reference

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

21 January 2018

1 reference

HELB Is a Feedback Inhibitor of DNA End Resection

21 January 2018

1 reference

Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress

21 January 2018

1 reference

Cell cycle-dependent regulation of a human DNA helicase that localizes in DNA damage foci

21 January 2018

1 reference

The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit

21 January 2018

1 reference

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

21 January 2018

1 reference

Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation

21 January 2018

1 reference

Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays

21 January 2018

1 reference

Pathways of DNA double-strand break repair during the mammalian cell cycle

21 January 2018

1 reference

Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase.

21 January 2018

1 reference

H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex

21 January 2018

1 reference

RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells

21 January 2018

1 reference

Identification of the MMS22L-TONSL complex that promotes homologous recombination

21 January 2018

1 reference

The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination

21 January 2018

1 reference

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

21 January 2018

1 reference

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

21 January 2018

1 reference

Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae.

21 January 2018

1 reference

Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells

21 January 2018

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Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin

21 January 2018

1 reference

Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

21 January 2018

1 reference

DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain

21 January 2018

1 reference

Specific recruitment of human cohesin to laser-induced DNA damage

21 January 2018

1 reference

The structural basis of modified nucleosome recognition by 53BP1

21 January 2018

1 reference

53BP1 regulates DSB repair using Rif1 to control 5' end resection

21 January 2018

1 reference

Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching

21 January 2018

1 reference

A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice

21 January 2018

1 reference

RIF1 counteracts BRCA1-mediated end resection during DNA repair

21 January 2018

1 reference

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.

21 January 2018

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Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage

21 January 2018

1 reference

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

21 January 2018

1 reference

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

21 January 2018

1 reference

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

21 January 2018

1 reference

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

21 January 2018

1 reference

A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency

21 January 2018

1 reference

BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair

21 January 2018

1 reference

Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection.

21 January 2018

1 reference

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

21 January 2018

1 reference

The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.

21 January 2018

1 reference

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

21 January 2018

1 reference

53BP1 fosters fidelity of homology-directed DNA repair

21 January 2018

1 reference

Causes and consequences of replication stress

21 January 2018

1 reference

Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase

21 January 2018

1 reference

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

21 January 2018

1 reference

The differences between ICL repair during and outside of S phase

21 January 2018

1 reference

Understanding nucleotide excision repair and its roles in cancer and ageing.

21 January 2018

1 reference

Replication-independent repair of DNA interstrand crosslinks

21 January 2018

1 reference

Functions of Ubiquitin and SUMO in DNA Replication and Replication Stress

21 January 2018

1 reference

The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase.

21 January 2018

1 reference

Ubiquitin-dependent DNA damage bypass is separable from genome replication

21 January 2018

1 reference

Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei

21 January 2018

1 reference

Aberrant chromosome morphology in human cells defective for Holliday junction resolution

21 January 2018

1 reference

Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis

21 January 2018

1 reference

Spatial control of the GEN1 Holliday junction resolvase ensures genome stability

21 January 2018

1 reference

Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability

21 January 2018

1 reference

The Cdk/cDc14 module controls activation of the Yen1 holliday junction resolvase to promote genome stability.

21 January 2018

1 reference

Holliday junction resolution: regulation in space and time

21 January 2018

1 reference

DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

21 January 2018

1 reference

21 January 2018

Chromosome fragile sites

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MUS81 promotes common fragile site expression.

21 January 2018

1 reference

ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis

21 January 2018

1 reference

Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease

21 January 2018

1 reference

Substrate specificity of the Saccharomyces cerevisiae Mus81-Mms4 endonuclease

21 January 2018

1 reference

Replication stress activates DNA repair synthesis in mitosis.

21 January 2018

1 reference

BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges

21 January 2018

1 reference

PICH: a DNA translocase specially adapted for processing anaphase bridge DNA.

21 January 2018

1 reference

Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability.

21 January 2018

1 reference

Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase

21 January 2018

1 reference

Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4

21 January 2018

1 reference

Kinetics of DNA Double-strand Break Repair Throughout the Cell Cycle as Assayed by Pulsed Field Gel Electrophoresis in CHO Cells

21 January 2018

1 reference

DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint

21 January 2018

1 reference

Spindle assembly checkpoint: the third decade

21 January 2018

1 reference

Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

1 reference

Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosomes in G1-phase or in condensed metaphase cells.

21 January 2018

1 reference

DNA damage signaling in response to double-strand breaks during mitosis

21 January 2018

1 reference

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint

21 January 2018

1 reference

Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation

21 January 2018

1 reference

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

21 January 2018

1 reference

A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair

21 January 2018

1 reference

DNA damage foci in mitosis are devoid of 53BP1.

21 January 2018

1 reference

Mitosis inhibits DNA double-strand break repair to guard against telomere fusions

21 January 2018

1 reference

Polo-like kinase 1 inhibits DNA damage response during mitosis

21 January 2018

1 reference

Dephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks

21 January 2018

1 reference

A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest

21 January 2018

1 reference

PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres

21 January 2018

1 reference

Cell death during crisis is mediated by mitotic telomere deprotection

21 January 2018

1 reference

Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair

21 January 2018

1 reference

The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry

21 January 2018

1 reference

Claspin: timing the cell cycle arrest when the genome is damaged

21 January 2018

1 reference

RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions.

21 January 2018

1 reference

RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage

21 January 2018

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CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

21 January 2018

1 reference

Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination

21 January 2018

1 reference

BubR1- and Polo-coated DNA tethers facilitate poleward segregation of acentric chromatids

21 January 2018

1 reference

Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events

21 January 2018

1 reference

Targeting the DNA Damage Response in Cancer

21 January 2018

1 reference

Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination

21 January 2018

2 references

12 December 2020

7 January 2021

Irradiation of parts of individual cells

2 references

12 December 2020

7 January 2021

Bloom's syndrome and EM9 cells in BrdU-containing medium exhibit similarly elevated frequencies of sister chromatid exchange but dissimilar amounts of cellular proliferation and chromosome disruption

2 references

12 December 2020

7 January 2021

The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination

1 reference

12 December 2020

PALB2: the hub of a network of tumor suppressors involved in DNA damage responses

1 reference

12 December 2020

Kinetochore localisation of the DNA damage response component 53BP1 during mitosis

1 reference

12 December 2020

Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction

2 references

12 December 2020

7 January 2021

Topoisomerase II inhibition prevents anaphase chromatid segregation in mammalian cells independently of the generation of DNA strand breaks.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCB3452

1 reference

8 September 2017

1 reference

PubMed ID

28008184