(Q39052443)

English

Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin

scientific article published on 28 November 2013

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scholarly article

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Europe PubMed Central

PMC publication ID

8 September 2017

Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin (English)

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Europe PubMed Central

PMC publication ID

8 September 2017

apoptotic process

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author name string

I Abd-Elrahman

1

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

V Deutsch

2

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

M Pick

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

S Kay

4

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

T Neuman

5

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

R Perlman

6

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

D Ben-Yehuda

7

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Europe PubMed Central

PMC publication ID

8 September 2017

language of work or name

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inferred from title

publication date

28 November 2013

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Europe PubMed Central

PMC publication ID

8 September 2017

Cell Death and Disease

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Europe PubMed Central

PMC publication ID

8 September 2017

4

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Europe PubMed Central

PMC publication ID

8 September 2017

e937

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

1 November 2013

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April 2022 Public Data File from Crossref

copyright status

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Caspase-3 is involved in the signalling in erythroid differentiation by targeting late progenitors.

1 reference

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Advances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside.

1 reference

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Non-apoptotic functions of apoptosis-regulatory proteins

1 reference

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9 September 2017

Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function

1 reference

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Apoptosis in the anucleate platelet

1 reference

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9 September 2017

Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

1 reference

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9 September 2017

The role of the intrinsic apoptosis pathway in platelet life and death.

1 reference

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Survivin is not required for the endomitotic cell cycle of megakaryocytes

1 reference

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A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia.

1 reference

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Programmed anuclear cell death delimits platelet life span.

1 reference

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9 September 2017

Subcellular localization determines the delicate balance between the anti- and pro-apoptotic activity of Livin

1 reference

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Differential requirements for survivin in hematopoietic cell development

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Megakaryocyte apoptosis: sorting out the signals

1 reference

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The inhibitor of apoptosis protein family (IAPs): an emerging therapeutic target in cancer

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Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene

1 reference

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Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction

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Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death

1 reference

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BclxL overexpression in megakaryocytes leads to impaired platelet fragmentation

1 reference

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IAP proteins: blocking the road to death's door

1 reference

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Roads to polyploidy: the megakaryocyte example

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Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

1 reference

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

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Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern

1 reference

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9 September 2017

Structural Basis of Caspase Inhibition by XIAP

1 reference

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Structural basis of caspase-7 inhibition by XIAP

1 reference

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ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

1 reference

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Livin, a novel inhibitor of apoptosis protein family member

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847330

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

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Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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Expansion of megakaryocyte progenitors from human umbilical cord blood using a new two-step separation procedure

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Transcription factor egr-1 is involved in phorbol 12-myristate 13-acetate-induced megakaryocytic differentiation of K562 cells

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Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

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Human chronic myeloid leukemic cell line with positive Philadelphia chromosome exhibits megakaryocytic and erythroid characteristics

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Selective triggering of platelet apoptosis, platelet activation or both.

1 reference

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Caspase inhibition decreases both platelet phosphatidylserine exposure and aggregation: caspase inhibition of platelets

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Platelet formation is the consequence of caspase activation within megakaryocytes

1 reference

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1 reference

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Omi/HtrA2 and XIAP are components of platelet apoptosis signalling

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In-vivo platelet activation correlates with red cell anionic phospholipid exposure in patients with beta-thalassaemia major

1 reference

https://pubmed.ncbi.nlm.nih.gov/24287698

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibitor of apoptosis protein Livin (ML-IAP) plays a dual role in tumorigenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24287698

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24287698

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low numbers of megakaryocyte progenitors in grafts of cord blood cells may result in delayed platelet recovery after cord blood cell transplant

1 reference

https://pubmed.ncbi.nlm.nih.gov/24287698

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CDDIS.2013.454

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

ResearchGate publication ID

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