(Q39054784)

8 September 2017

title

The expression and prognosis of Emi1 and Skp2 in breast carcinoma: associated with PI3K/Akt pathway and cell proliferation (English)

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8 September 2017

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Xiaobing Liu

1

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8 September 2017

Hua Wang

2

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8 September 2017

Jing Ma

3

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8 September 2017

Junfei Xu

4

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8 September 2017

Chenyi Sheng

5

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8 September 2017

Shuyun Yang

6

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8 September 2017

Lingling Sun

7

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8 September 2017

Qichao Ni

8

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8 September 2017

publication date

25 October 2013

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8 September 2017

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8 September 2017

volume

30

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8 September 2017

issue

4

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8 September 2017

page(s)

735

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Global cancer statistics, 2002

8 September 2017

cites work

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https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

21 January 2018

Global cancer statistics

1 reference

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Cyclins and cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Emi1 protein accumulation implicates misregulation of the anaphase promoting complex/cyclosome pathway in ovarian clear cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Gene expression patterns in ovarian carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Alterations of anaphase-promoting complex genes in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

The mTOR inhibitor rapamycin down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Skp2 is oncogenic and overexpressed in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Prognostic impact of Skp2 and p27 in human breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Relationship between levels of Skp2 and P27 in breast carcinomas and possible role of Skp2 as targeted therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state

21 January 2018

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Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Cytoplasmic Skp2 expression is associated with p-Akt1 and predicts poor prognosis in human breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

The APC/C inhibitor, Emi1, is essential for prevention of rereplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

The cyclin dependent kinase inhibitor p27 and its prognostic role in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Akt activation promotes degradation of tuberin and FOXO3a via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0735-0

Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy

21 January 2018

1 reference

12 December 2020

The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling

1 reference

12 December 2020

Tumor necrosis factor alpha induces BID cleavage and bypasses antiapoptotic signals in prostate cancer LNCaP cells.

1 reference

12 December 2020

p27 expression and gastric carcinoma

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12 December 2020

Clinical and biological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma: modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis

1 reference

12 December 2020

Estimation of the proliferative activity of human breast cancer tissue by means of the Ki-67 and MIB-1 antibodies ? comparative studies on frozen and paraffin sections

1 reference

12 December 2020

Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival.

1 reference

12 December 2020

10.1007/S12032-013-0735-0

Identifiers

DOI

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8 September 2017

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