(Q39071496)

English

Interleukin-12 modulates T-cell responses to microfilariae but fails to abrogate interleukin-5-dependent immunity in a mouse model of onchocerciasis

scientific article published on November 1999

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

Interleukin-12 modulates T-cell responses to microfilariae but fails to abrogate interleukin-5-dependent immunity in a mouse model of onchocerciasis (English)

1 reference

Europe PubMed Central

8 September 2017

0 references

0 references

author name string

P J Hogarth

1

1 reference

Europe PubMed Central

8 September 2017

A E Bianco

2

1 reference

Europe PubMed Central

8 September 2017

publication date

1 November 1999

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

98

1 reference

Europe PubMed Central

8 September 2017

3

1 reference

Europe PubMed Central

8 September 2017

406-412

1 reference

Europe PubMed Central

8 September 2017

IL-5 dominates cytokine responses during expression of protective immunity to Onchocerca lienalis microfilariae in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

IL-5-dependent immunity to microfilariae is independent of IL-4 in a mouse model of onchocerciasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Protective responses against skin-dwelling microfilariae of Onchocerca lienalis in severe combined immunodeficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Eosinophils and eosinophil-associated cytokines in allergic inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Accelerated clearance of Onchocerca microfilariae and resistance to reinfection in interleukin-4 gene knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Eosinophils are the major effector cells of immunity to microfilariae in a mouse model of onchocerciasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Immunoregulation in onchocerciasis: predominance of Th1-type responsiveness to low molecular weight antigens of Onchocerca volvulus in exposed individuals without microfilaridermia and clinical disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Roles for both CD4+ and CD8+ T cells in protective immunity against Onchocerca lienalis microfilariae in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Ablation of eosinophils with anti-IL-5 antibody enhances the survival of intracranial worms of Angiostrongylus cantonensis in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Cytokine-mediated regulation of chronic intestinal helminth infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Immune responsiveness and the pathogenesis of human onchocerciasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

IL-12 modulation of T helper responses to the filarial helminth, Brugia malayi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Interleukin 4 and T helper type 2 cells are required for development of experimental onchocercal keratitis (river blindness).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Cellular killing of microfilariae of Onchocerca volvulus: eosinophil and neutrophil-mediated immune serum-dependent destruction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Variations in host responses and the pathogenesis of human onchocerciasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Fate of developing larvae of Onchocerca lienalis and O. volvulus in micropore chambers implanted into laboratory hosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

The role of interleukin-5 in protective immunity to Strongyloides venezuelensis infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Patterns of cytokine production and proliferation by T lymphocytes differ in mice vaccinated or infected with Schistosoma mansoni.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Lymphokine control of in vivo immunoglobulin isotype selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Regulation of immunity to parasites by T cells and T cell-derived cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

T cell-derived cytokines associated with pulmonary immune mechanisms in mice vaccinated with irradiated cercariae of Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

The importance of Th2 cytokines in protective immunity to nematodes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Role of IL-4 and IFN-gamma in Schistosoma mansoni egg-induced hypersensitivity granuloma formation. Orchestration, relative contribution, and relationship to macrophage function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2326952

15 September 2018

Impaired immunity and altered pulmonary responses in mice with a disrupted interferon-gamma receptor gene exposed to the irradiated Schistosoma mansoni vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schistosoma mansoni in IL-4-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoregulation in onchocerciasis: persons with ocular inflammatory disease produce a Th2-like response to Onchocerca volvulus antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Onchocerca volvulus-mediated keratitis: cytokine production by IL-4-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental infection of mice with the microfilariae of Onchocerca lienalis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of IL-5 in IL-2-induced eosinophilia. In vivo and in vitro expression of IL-5 mRNA by IL-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 exacerbates helminth-mediated corneal pathology by augmenting inflammatory cell recruitment and chemokine expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 eliminates the Th-2 dependent protective immune response of mice to larval Strongyloides stercoralis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of IL-5 in onchocerciasis. A critical role for IL-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunity to onchocerciasis: putative immune persons produce a Th1-like response to Onchocerca volvulus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Onchocerciasis and its control. Report of a WHO Expert Committee on Onchocerciasis Control

1 reference

https://pubmed.ncbi.nlm.nih.gov/10583601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2567.1999.00891.X

1 reference

Europe PubMed Central

8 September 2017

0 references

1 reference

Europe PubMed Central

8 September 2017

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0 references

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