(Q39085744)

8 September 2017

title

Phosphorylation of paxillin confers cisplatin resistance in non-small cell lung cancer via activating ERK-mediated Bcl-2 expression (English)

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non-small-cell lung carcinoma

8 September 2017

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D-W Wu

1

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8 September 2017

T-C Wu

2

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8 September 2017

J-Y Wu

3

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8 September 2017

Y-W Cheng

4

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8 September 2017

Y-C Chen

5

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8 September 2017

M-C Lee

6

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8 September 2017

C-Y Chen

7

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8 September 2017

H Lee

8

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8 September 2017

language of work or name

English

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publication date

7 October 2013

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8 September 2017

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8 September 2017

volume

33

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8 September 2017

issue

35

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8 September 2017

page(s)

4385-4395

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Activation of platelet-activating factor receptor and pleiotropic effects on tyrosine phospho-EGFR/Src/FAK/paxillin in ovarian cancer

8 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

21 January 2018

Paxillin comes of age

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

JNK phosphorylates paxillin and regulates cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Short interfering RNA directed against TWIST, a novel zinc finger transcription factor, increases A549 cell sensitivity to cisplatin via MAPK/mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Paxillin mediates extranuclear and intranuclear signaling in prostate cancer proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

CREB mediates ERK-induced survival of mouse renal tubular cells after oxidant stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Evidence for involvement of ERK, PI3K, and RSK in induction of Bcl-2 by valproate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Up-regulation of Bcl-2 through ERK phosphorylation is associated with human macrophage survival in an estrogen microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Paxillin's LD4 motif interacts with bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Interaction of bcl-2 with Paxillin through its BH4 domain is important during ureteric bud branching

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Paxillin is a novel cellular target for converging Helicobacter pylori-induced cellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Paxillin contracts the osteoclast cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Simultaneous targeting of Src kinase and receptor tyrosine kinase results in synergistic inhibition of renal cell carcinoma proliferation and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

CREB-mediated Bcl-2 protein expression after ischemic preconditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Inhibition of Src impairs the growth of met-addicted gastric tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Bcl-2 family proteins contribute to apoptotic resistance in lung cancer multicellular spheroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

A small molecule pan-Bcl-2 family inhibitor, GX15-070, induces apoptosis and enhances cisplatin-induced apoptosis in non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Bcl-2 as a predictor of chemosensitivity and prognosis in primary epithelial ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Overexpression of Bcl-2 in bladder cancer cells inhibits apoptosis induced by cisplatin and adenoviral-mediated p53 gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Bcl-2 modulation to activate apoptosis in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Suppression of BCL-2 synergizes cisplatin sensitivity in nasopharyngeal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Loss of TIMP-3 promotes tumor invasion via elevated IL-6 production and predicts poor survival and relapse in HPV-infected non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Reduced p21(WAF1/CIP1) via alteration of p53-DDX3 pathway is associated with poor relapse-free survival in early-stage human papillomavirus-associated lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

Epithelial to mesenchymal transition is a determinant of sensitivity to chemoradiotherapy in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.389

A polymorphic -844T/C in FasL promoter predicts survival and relapse in non-small cell lung cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2013.389

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.389

1 reference

8 September 2017

1 reference