(Q39094539)

9 September 2017

Benchmarking of multivariate similarity measures for high-content screening fingerprints in phenotypic drug discovery (English)

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9 September 2017

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multivariate statistics

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1 reference

Felix Reisen

1

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9 September 2017

Xian Zhang

series ordinal

2

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9 September 2017

Daniela Gabriel

series ordinal

3

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9 September 2017

Paul Selzer

series ordinal

4

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9 September 2017

17 September 2013

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Journal of Biomolecular Screening

9 September 2017

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9 September 2017

18

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9 September 2017

1284-1297

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9 September 2017

10

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The beautiful cell: high-content screening in drug discovery

9 September 2017

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

How were new medicines discovered?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Small molecule regulators of autophagy identified by an image-based high-throughput screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Chemical genetic analysis of FOXO nuclear-cytoplasmic shuttling by using image-based cell screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Differentiation and visualization of diverse cellular phenotypic responses in primary high-content screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Robust hit identification by quality assurance and multivariate data analysis of a high-content, cell-based assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Multidimensional drug profiling by automated microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Development of a high-content screening assay panel to accelerate mechanism of action studies for oncology research

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Compound classification using image-based cellular phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

An unbiased cell morphology-based screen for new, biologically active small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Integrating high-content screening and ligand-target prediction to identify mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Integration of multiple readouts into the z' factor for assay quality assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Kernelized Z' factor in multiparametric screening technology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

A robust high-content imaging approach for probing the mechanism of action and phenotypic outcomes of cell-cycle modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

An approach for extensibly profiling the molecular states of cellular subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Measuring and testing dependence by correlation of distances

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Detecting novel associations in large data sets

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Unsupervised Learning With Random Forest Predictors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Comparison of multivariate data analysis strategies for high-content screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Evaluating virtual screening methods: good and bad metrics for the "early recognition" problem.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Extended-connectivity fingerprints

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

Performance evaluation of 2D fingerprint and 3D shape similarity methods in virtual screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113501390

21 January 2018

Identifiers

DOI

10.1177/1087057113501390

1 reference

9 September 2017

1 reference