(Q39103125)

English

Synthesis of saxitoxin derivatives bearing guanidine and urea groups at C13 and evaluation of their inhibitory activity on voltage-gated sodium channels

scientific article published on 30 August 2013

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scholarly article

1 reference

Europe PubMed Central

9 September 2017

Synthesis of saxitoxin derivatives bearing guanidine and urea groups at C13 and evaluation of their inhibitory activity on voltage-gated sodium channels (English)

1 reference

Europe PubMed Central

9 September 2017

author name string

Takafumi Akimoto

1

1 reference

Europe PubMed Central

9 September 2017

Asako Masuda

2

1 reference

Europe PubMed Central

9 September 2017

Mari Yotsu-Yamashita

3

1 reference

Europe PubMed Central

9 September 2017

Takatsugu Hirokawa

4

1 reference

Europe PubMed Central

9 September 2017

Kazuo Nagasawa

5

1 reference

Europe PubMed Central

9 September 2017

publication date

30 August 2013

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Europe PubMed Central

9 September 2017

Organic and Biomolecular Chemistry

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Europe PubMed Central

9 September 2017

11

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Europe PubMed Central

9 September 2017

6642-6649

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Europe PubMed Central

9 September 2017

38

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Europe PubMed Central

9 September 2017

Voltage-dependent blockade of muscle Na+ channels by guanidinium toxins

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Voltage-gated sodium channels as therapeutic targets

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Existence of distinct sodium channel messenger RNAs in rat brain

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Functional modulation of human brain Nav1.3 sodium channels, expressed in mammalian cells, by auxiliary beta 1, beta 2 and beta 3 subunits

1 reference

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21 January 2018

Primary structure and functional expression of a mammalian skeletal muscle sodium channel

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Functional expression and properties of the human skeletal muscle sodium channel

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A novel tetrodotoxin-sensitive, voltage-gated sodium channel expressed in rat and human dorsal root ganglia.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A cation-pi interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Structure and function of a novel voltage-gated, tetrodotoxin-resistant sodium channel specific to sensory neurons.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

NaN/Nav1.9: a sodium channel with unique properties

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Marked difference in saxitoxin and tetrodotoxin affinity for the human nociceptive voltage-gated sodium channel (Nav1.7) [corrected]

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Hyperkalemic periodic paralysis and the adult muscle sodium channel alpha-subunit gene

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Genotype-phenotype correlation and therapeutic rationale in hyperkalemic periodic paralysis

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

An SCN9A channelopathy causes congenital inability to experience pain

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A case of inherited erythromelalgia

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Total synthesis of (-)- and (+)-decarbamoyloxysaxitoxin and (+)-saxitoxin

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Total synthesis of (+)-decarbamoylsaxitoxin and (+)-gonyautoxin 3.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Synthesis of skeletal analogues of saxitoxin derivatives and evaluation of their inhibitory activity on sodium ion channels Na(V)1.4 and Na(V)1.5.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligands

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Energetic localization of saxitoxin in its channel binding site.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

The crystal structure of a voltage-gated sodium channel

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Saxitoxin, a toxic marine natural product that targets a multitude of receptors

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

An improved procedure for the Blaise reaction: a short, practical route to the key intermediates of the saxitoxin synthesis

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A stereospecific total synthesis of dl-saxitoxin

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A synthesis of (+)-saxitoxin

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

(+)-saxitoxin: a first and second generation stereoselective synthesis

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A stereocontrolled synthesis of (+)-saxitoxin.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A stereoselective synthesis of (+)-gonyautoxin 3.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

The potencies of synthetic analogues of saxitoxin and the absolute stereoselectivity of decarbamoyl saxitoxin.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

De novo synthesis of modified saxitoxins for sodium ion channel study

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Synthesis of bifunctional saxitoxin analogues by biotinylation

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Novel modulator of Na(V)1.1 and Na(V)1.2 Na channels in rat neuronal cells

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Routes to functionalized guanidines. The synthesis of guanidino diesters.

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

A tissue culture assay for tetrodotoxin, saxitoxin and related toxins

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Tetrazolium-based cell bioassay for neurotoxins active on voltage-sensitive sodium channels: semiautomated assay for saxitoxins, brevetoxins, and ciguatoxins

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

Biological activity of 8,11-dideoxytetrodotoxin: lethality to mice and the inhibitory activity to cytotoxicity of ouabain and veratridine in mouse neuroblastoma cells, Neuro-2a

1 reference

https://api.crossref.org/works/10.1039%2FC3OB41398E

21 January 2018

China must provide education on HIV

1 reference

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21 January 2018

Identifiers

10.1039/C3OB41398E

1 reference

Europe PubMed Central

9 September 2017

1 reference

Europe PubMed Central

9 September 2017

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