(Q39107527)

English

The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity.

scientific article published on October 2013

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23963286%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23963286%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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Alejandro Villagra

12

1 reference

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7 March 2020

author name string

David M Woods

1

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7 March 2020

Karrune Woan

2

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7 March 2020

Fengdong Cheng

3

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7 March 2020

Hongwei Wang

4

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7 March 2020

Patricio Perez-Villarroel

5

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7 March 2020

Calvin Lee

6

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7 March 2020

Maritza Lienlaf

7

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7 March 2020

Peter Atadja

8

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7 March 2020

Edward Seto

9

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7 March 2020

Jeffrey Weber

10

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7 March 2020

Eduardo M Sotomayor

11

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7 March 2020

language of work or name

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publication date

1 October 2013

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7 March 2020

Melanoma Research

1 reference

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7 March 2020

23

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7 March 2020

5

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7 March 2020

341-348

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7 March 2020

Cancer statistics, 2013

1 reference

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The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms

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Modulation of antigen-presenting cells by HDAC inhibitors: implications in autoimmunity and cancer

1 reference

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9 September 2017

Histone deacetylase inhibitor LAQ824 augments inflammatory responses in macrophages through transcriptional regulation of IL-10.

1 reference

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9 September 2017

The clinical development of histone deacetylase inhibitors as targeted anticancer drugs

1 reference

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9 September 2017

HDAC4 inhibits the transcriptional activation of mda-7/IL-24 induced by Sp1.

1 reference

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9 September 2017

Enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

9 September 2017

Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials

1 reference

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9 September 2017

B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells

1 reference

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9 September 2017

Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

9 September 2017

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

9 September 2017

Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

9 September 2017

Production of IL-10 by melanoma cells: examination of its role in immunosuppression mediated by melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

9 September 2017

Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

14 September 2017

Histone deacetylase inhibitors induce G2-checkpoint arrest and apoptosis in cisplatinum-resistant ovarian cancer cells associated with overexpression of the Bcl-2-related protein Bad.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

14 September 2017

The antigen specific composition of melanoma tumor infiltrating lymphocytes?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

15 June 2018

Expression of the co-stimulatory molecule B7 on melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

15 June 2018

Overexpression and immunosuppressive functions of transforming growth factor 1, vascular endothelial growth factor and interleukin-10 in epithelial ovarian cancer

1 reference

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21 August 2018

Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

21 August 2018

Low-dose IFN-gamma induces tumor MHC expression in metastatic malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012016

21 August 2018

Phase I trial of a B7-1 (CD80) gene modified autologous tumor cell vaccine in combination with systemic interleukin-2 in patients with metastatic renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23963286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss or downregulation of HLA class I expression at the allelic level in acute leukemia is infrequent but functionally relevant, and can be restored by interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/23963286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/23963286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/CMR.0B013E328364C0ED

1 reference

Europe PubMed Central

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7 March 2020

release_nnk6xnbp3jgwdhlrgpkkvmysnu

1 reference

https://api.fatcat.wiki/v0/release/nnk6xnbp3jgwdhlrgpkkvmysnu

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23963286%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23963286%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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