(Q39117991)

9 September 2017

title

Synthesis and activity of 2-(sulfonamido)methyl-carbapenems: discovery of a novel, anti-MRSA 1,8-naphthosultam pharmacophore (English)

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9 September 2017

main subject

carbapenem antibiotic

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author name string

Wilkening RR

1

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9 September 2017

Ratcliffe RW

2

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9 September 2017

Wildonger KJ

3

1 reference

9 September 2017

Cama LD

4

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9 September 2017

Dykstra KD

5

1 reference

9 September 2017

DiNinno FP

6

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9 September 2017

Blizzard TA

7

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9 September 2017

Hammond ML

8

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9 September 2017

Heck JV

9

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9 September 2017

Dorso KL

10

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9 September 2017

St Rose E

11

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9 September 2017

Kohler J

12

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9 September 2017

Hammond GG

13

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9 September 2017

language of work or name

English

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publication date

1 March 1999

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Bioorganic & Medicinal Chemistry Letters

9 September 2017

published in

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9 September 2017

volume

9

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9 September 2017

issue

5

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9 September 2017

page(s)

673-678

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Colonisation and infection with resistant gram-positive cocci. Epidemiology and risk factors.

9 September 2017

cites work

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7 January 2021

Gram-positive resistance: challenge for the development of new antibiotics

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7 January 2021

Methicillin-resistant Staphylococus aureus and vancomycin-resistant enterococci: therapeutic realities and possibilities

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7 January 2021

Antimicrobial resistance in staphylococci. Epidemiology, molecular mechanisms, and clinical relevance

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7 January 2021

Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications.

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Anti-gram-positive agents. What we have and what we would like.

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7 January 2021

Vancomycin-resistant enterococci

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7 January 2021

Vancomycin-resistant enterococci

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7 January 2021

Vancomycin-resistant Staphylococcus aureus: perspectives on measures needed for control

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7 January 2021

Vancomycin-resistant Staphylococcus aureus: apocalypse now?

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Structure-activity relationships of cephalosporin derivatives against methicillin-resistant Staphylococcus aureus and Enterococcus faecalis

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7 January 2021

Discovery and structure-activity relationship of a series of 1-carba-1-dethiacephems exhibiting activity against methicillin-resistant Staphylococcus aureus

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7 January 2021

Synthesis and biological properties of a series of optically active 2-oxaisocephems.

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7 January 2021

Structure-Activity Relationships of 2-Thioisocephem against Methicillin-resistant Staphylococcus aureus

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7 January 2021

5,6-cis-Penems: Broad-Spectrum Anti-Methicillin-Resistant Staphylococcus aureus β-Lactam Antibiotics

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7 January 2021

Synthesis and biological properties of a new series of anti-MRSA beta-lactams; 2-(thiazol-2-ylthio)carbapenems

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7 January 2021

Novel dithiocarbamate carbapenems with anti-MRSA activity

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7 January 2021

Synthesis and antibacterial activity of novel 4-pyrrolidinylthio carbapenems II: 2-alkyl and 2-arylthiomethyl derivatives

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7 January 2021

In vitro and in vivo antistaphylococcal activities of L-695,256, a carbapenem with high affinity for the penicillin-binding protein PBP 2a.

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7 January 2021

Comparative in vitro activities of L-695,256, a novel carbapenem, against gram-positive bacteria

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7 January 2021

Binding of beta-lactam antibiotics to penicillin-binding proteins in methicillin-resistant Staphylococcus aureus.

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7 January 2021

Molecular aspects of methicillin resistance in Staphylococcus aureus

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7 January 2021

Overproduction of a low-affinity penicillin-binding protein and high-level ampicillin resistance in Enterococcus faecium

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7 January 2021

Species specificity of 2-aryl carbapenem-induced immune-mediated hemolytic anemia in primates

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7 January 2021

Mechanism of inhibition of the PC1 beta-lactamase of Staphylococcus aureus by cephalosporins: importance of the 3'-leaving group

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7 January 2021

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7 January 2021

The synthesis of 2-(functionalized methyl)-1.BETA.-methylcarbapenems

1 reference

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7 January 2021

Soluble penicillin-binding protein 2a: beta-lactam binding and inhibition by non-beta-lactams using a 96-well format

1 reference

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7 January 2021

Synthesis and properties of 2-(naphthosultamyl)methyl-carbapenems with potent anti-MRSA activity: discovery of L-786,392.

1 reference

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7 January 2021

10.1016/S0960-894X(99)00070-0

Identifiers

DOI

1 reference

9 September 2017

1 reference