(Q39127471)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

2

1 reference

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22 January 2020

David A. Horn

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Fredrik Björkling

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

John M Kelly

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Einars Loza

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Ivars Kalvinsh

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

28 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

Bioorganic & Medicinal Chemistry Letters

22 January 2020

published in

1 reference

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22 January 2020

volume

22

1 reference

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22 January 2020

issue

5

1 reference

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22 January 2020

page(s)

1886-1890

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

Histone deacetylases as regulators of inflammation and immunity

22 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

The therapeutic potential of HDAC inhibitors in the treatment of multiple sclerosis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Molecular mechanisms underlying the control of antigenic variation in African trypanosomes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

A structure-activity relationship study of the antimalarial and antileishmanial activities of nonpeptide macrocyclic histone deacetylase inhibitors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Histone H3 lysine 4 di-methylation: a novel mark for transcriptional fidelity?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Targeting histone deacetylase inhibitors for anti-malarial therapy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

The burden of human African trypanosomiasis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

The continuing problem of human African trypanosomiasis (sleeping sickness).

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Histone H3 lysine 56 acetylation: a new twist in the chromosome cycle

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Histone deacetylases in Trypanosoma brucei: two are essential and another is required for normal cell cycle progression.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Cloning and characterization of a novel human histone deacetylase, HDAC8

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

The rise and fall of sleeping sickness

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Structural Biasing Elements for In-Cell Histone Deacetylase Paralog Selectivity

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314994

Novel amide derivatives as inhibitors of histone deacetylase: design, synthesis and SAR

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22326398

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2012.01.072

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

22326398

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22326398%20AND%20SRC:MED&resulttype=core&format=json