(Q39129185)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Impact of Stereochemistry on Ligand Binding: X-ray Crystallographic Analysis of an Epoxide-Based HIV Protease Inhibitor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Federico Berti

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Lidia Fanfoni

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Nicola Demitri

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Folasade M Olajuyigbe

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Matteo De March

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Silvano Geremia

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Pietro Campaner

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

publication date

14 July 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

ACS Medicinal Chemistry Letters

16 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

968-972

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

Carbamylation of N-Terminal Proline

16 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

The early years of retroviral protease crystal structures.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Survival trends in critically ill HIV-infected patients in the highly active antiretroviral therapy era.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Drug resistance mutations for surveillance of transmitted HIV-1 drug-resistance: 2009 update

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Development of protease inhibitors and the fight with drug-resistant HIV-1 variants

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Design of HIV protease inhibitors targeting protein backbone: an effective strategy for combating drug resistance

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

HIV-1 protease: mechanism and drug discovery

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Structural implications of drug-resistant mutants of HIV-1 protease: high-resolution crystal structures of the mutant protease/substrate analogue complexes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Active human immunodeficiency virus protease is required for viral infectivity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Specific and irreversible inactivation of pepsin by substrate-like epoxides.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Theoretical study on the mechanism of a ring-opening reaction of oxirane by the active-site aspartic dyad of HIV-1 protease.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Alkylation of a catalytic aspartate group of the SIV protease by an epoxide inhibitor

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

A Potent HIV Protease Inhibitor Identified in an Epimeric Mixture by High-Resolution Protein Crystallography

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4160752

Prevalence of darunavir resistance mutations in HIV-1-infected patients failing other protease inhibitors

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25221650

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML500092E

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221650%20AND%20SRC:MED&resulttype=core&format=json