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English
Targeting mTOR in RET mutant medullary and differentiated thyroid cancer cells.
scientific article published on 21 August 2013
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
title
Targeting mTOR in RET mutant medullary and differentiated thyroid cancer cells
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
main subject
differentiated thyroid carcinoma
1 reference
based on heuristic
inferred from title
author
Iñigo Landa
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
Jeffrey A Knauf
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
author name string
Matti L Gild
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
Mabel Ryder
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
Ronald A Ghossein
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
James A Fagin
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
21 August 2013
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
published in
Endocrine-Related Cancer
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
volume
20
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
page(s)
659-667
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
cites work
Novel withanolides target medullary thyroid cancer through inhibition of both RET phosphorylation and the mammalian target of rapamycin pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
9 September 2017
Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
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9 September 2017
Defining the role of TORC1/2 in multiple myeloma
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
9 September 2017
Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
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9 September 2017
Synergistic action of a RAF inhibitor and a dual PI3K/mTOR inhibitor in thyroid cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
9 September 2017
Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
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9 September 2017
Everolimus for advanced pancreatic neuroendocrine tumors.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
9 September 2017
Targeting the PI3K/mTOR pathway in murine endocrine cell lines: in vitro and in vivo effects on tumor cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
9 September 2017
Vandetanib (100 mg) in patients with locally advanced or metastatic hereditary medullary thyroid cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
9 September 2017
Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
9 September 2017
Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
9 September 2017
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
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9 September 2017
Dysregulated RET signaling in thyroid cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
9 September 2017
BRAFV600E mutation is associated with preferential sensitivity to mitogen-activated protein kinase kinase inhibition in thyroid cancer cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
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9 September 2017
RET as a diagnostic and therapeutic target in sporadic and hereditary endocrine tumors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
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9 September 2017
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
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9 September 2017
The GDNF family: signalling, biological functions and therapeutic value
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
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9 September 2017
The rapamycin-derivative RAD001 (everolimus) inhibits cell viability and interacts with the Akt-mTOR-p70S6K pathway in human medullary thyroid carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
14 September 2017
Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
14 September 2017
The RET kinase inhibitor NVP-AST487 blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
14 September 2017
Apoptosis-mediated medullary thyroid cancer growth suppression by the PI3K inhibitor LY294002.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
14 September 2017
Misidentification of putative medullary thyroid cancer cell lines RO-H85-1 and RO-D81-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
21 August 2018
Mammalian target of rapamycin pathway activation is associated to RET mutation status in medullary thyroid carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375728
retrieved
21 August 2018
The RET/PTC3 oncogene: metastatic solid-type papillary carcinomas in murine thyroids
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23828865
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1530/ERC-13-0085
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
PMCID
4375728
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
PubMed ID
23828865
1 reference
stated in
Europe PubMed Central
PMCID
4375728
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23828865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
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