(Q39133110)

9 September 2017

title

Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter (English)

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9 September 2017

author name string

Carolien M S Schophuizen

1

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9 September 2017

Martijn J Wilmer

2

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9 September 2017

Jitske Jansen

3

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9 September 2017

Lena Gustavsson

4

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9 September 2017

Constanze Hilgendorf

5

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9 September 2017

Joost G J Hoenderop

6

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9 September 2017

Lambert P van den Heuvel

7

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9 September 2017

Rosalinde Masereeuw

8

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9 September 2017

publication date

29 June 2013

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9 September 2017

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9 September 2017

volume

465

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9 September 2017

issue

12

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9 September 2017

page(s)

1701-1714

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Endogenous gene and protein expression of drug-transporting proteins in cell lines routinely used in drug discovery programs

9 September 2017

cites work

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Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2

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Normal and pathologic concentrations of uremic toxins

21 January 2018

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Impact of increasing haemodialysis frequency versus haemodialysis duration on removal of urea and guanidino compounds: a kinetic analysis

21 January 2018

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Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants

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Cloning and characterization of two human polyspecific organic cation transporters

21 January 2018

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Roles of organic anion/cation transporters at the blood-brain and blood-cerebrospinal fluid barriers involving uremic toxins

21 January 2018

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Modulation of cellular function by polyamines

21 January 2018

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Polyamines in renal failure.

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The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule

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Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2.

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Metformin transport by renal basolateral organic cation transporter hOCT2.

21 January 2018

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Protein-bound uraemic toxin removal in haemodialysis and post-dilution haemodiafiltration

21 January 2018

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Polyamines in the anemia of end-stage renal disease

21 January 2018

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If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?

21 January 2018

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Effects of guanidino and uremic compounds on nitric oxide pathways

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

21 January 2018

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Altered nonrenal drug clearance in ESRD.

21 January 2018

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Identification of Spermine as an Inhibitor of Erythropoiesis in Patients with Chronic Renal Failure

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21 January 2018

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Acrolein produced from polyamines as one of the uraemic toxins

21 January 2018

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Increase in putrescine, amine oxidase, and acrolein in plasma of renal failure patients.

21 January 2018

1 reference

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The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.

21 January 2018

1 reference

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Polyamine cytotoxicity in the presence of bovine serum amine oxidase

21 January 2018

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21 January 2018

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21 January 2018

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Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2

21 January 2018

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Calmodulin-associated post-translational regulation of rat organic cation transporter 2 in the kidney is gender dependent

21 January 2018

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Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters

21 January 2018

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OCT2 and MATE1 provide bidirectional agmatine transport

21 January 2018

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Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2).

21 January 2018

1 reference

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Serum guanidino compound levels in uremic pediatric patients treated with hemodialysis or continuous cycle peritoneal dialysis. Correlations between nerve conduction velocities and altered guanidino compound concentrations

21 January 2018

1 reference

12 December 2020

Alteration of drug-protein binding in renal disease

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12 December 2020

The removal of uremic toxins.

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12 December 2020

Evidence that guanidines and some related compounds cause haemolysis in chronic uraemia

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12 December 2020

Pathophysiologic effects of uremic retention solutes.

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12 December 2020

Intracellular location of polyamines associated to red blood cells

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12 December 2020

Uraemic guanidino compounds inhibit gamma-aminobutyric acid-evoked whole cell currents in mouse spinal cord neurones

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12 December 2020

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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12 December 2020

Direct inhibitory effect of uremic toxins and polyamines on proliferation of VERO culture cells

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12 December 2020

Determination of polyamines in hydrolysates of uremic plasma by high-performance cation-exchange column chromatography

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12 December 2020

Uremic toxicity of indoxyl sulfate

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12 December 2020

10.1007/S00424-013-1307-Z

Identifiers

DOI

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9 September 2017

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