(Q39135479)

9 September 2017

title

Free light chain content in culture media reflects recombinant monoclonal antibody productivity and quality (English)

1 reference

9 September 2017

1 reference

Prachi Bhoskar

1

1 reference

9 September 2017

Brett Belongia

2

1 reference

9 September 2017

Robert Smith

3

1 reference

9 September 2017

Seongkyu Yoon

4

1 reference

9 September 2017

Tyler Carter

5

1 reference

9 September 2017

Jin Xu

6

1 reference

9 September 2017

publication date

25 June 2013

1 reference

9 September 2017

published in

Biotechnology Progress

1 reference

9 September 2017

volume

29

1 reference

9 September 2017

issue

5

1 reference

9 September 2017

page(s)

1131-1139

1 reference

Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals

9 September 2017

cites work

1 reference

mAbs: a business perspective

21 January 2018

1 reference

Recombinant protein expression for therapeutic applications

21 January 2018

1 reference

Industrial choices for protein production by large-scale cell culture

21 January 2018

1 reference

Cell culture processes for monoclonal antibody production

21 January 2018

1 reference

Development and production of commercial therapeutic monoclonal antibodies in Mammalian cell expression systems: an overview of the current upstream technologies

21 January 2018

1 reference

Analysis of changes during subclone development and ageing of human antibody-producing heterohybridoma cells by northern blot and flow cytometry.

21 January 2018

1 reference

Correlation of heavy and light chain mRNA copy numbers to antibody productivity in mouse myeloma production cell lines

21 January 2018

1 reference

Regulation of recombinant monoclonal antibody production in chinese hamster ovary cells: a comparative study of gene copy number, mRNA level, and protein expression.

21 January 2018

1 reference

A clone screening method using mRNA levels to determine specific productivity and product quality for monoclonal antibodies

21 January 2018

1 reference

On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells.

21 January 2018

1 reference

A structured model for monoclonal antibody synthesis in exponentially growing and stationary phase hybridoma cells

21 January 2018

1 reference

Analysis of IgG heavy chain to light chain ratio with mutant Encephalomyocarditis virus internal ribosome entry site

21 January 2018

1 reference

A mouse myeloma variant with a defect in light chain synthesis

21 January 2018

1 reference

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas

21 January 2018

1 reference

Molecular chaperones in cellular protein folding

21 January 2018

1 reference

Assembly of immunoglobulin light chains as a prerequisite for secretion. A model for oligomerization-dependent subunit folding

21 January 2018

1 reference

BiP and immunoglobulin light chain cooperate to control the folding of heavy chain and ensure the fidelity of immunoglobulin assembly

21 January 2018

1 reference

Funnels, pathways, and the energy landscape of protein folding: a synthesis

21 January 2018

1 reference

Protein folding and modification in the mammalian endoplasmic reticulum.

21 January 2018

1 reference

A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins

21 January 2018

1 reference

Quality control in the endoplasmic reticulum

21 January 2018

1 reference

Endoplasmic reticulum stress: cell life and death decisions.

21 January 2018

1 reference

Induction of protein aggregation in an early secretory compartment by elevation of expression level

21 January 2018

1 reference

Principles of protein folding, misfolding and aggregation

21 January 2018

1 reference

Unassembled Ig heavy chains do not cycle from BiP in vivo but require light chains to trigger their release

21 January 2018

1 reference

Enhancing effect of low culture temperature on specific antibody productivity of recombinant Chinese hamster ovary cells: clonal variation.

21 January 2018

1 reference

Protein aggregation and bioprocessing

21 January 2018

1 reference

Demethylation of the zygotic paternal genome

21 January 2018

1 reference

Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum

21 January 2018

1 reference

Synthesis of Excess Light Chains of Gamma Globulin by Rabbit Lymph Node Cells

21 January 2018

1 reference

Biosynthesis of Immunoglobulins. Free Light Chain as an Intermediate in the Assembly of γG-Molecules

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/BTPR.1767

1 reference

9 September 2017

1 reference