(Q39148603)

English

Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells.

scientific article published on 18 April 2013

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698071%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698071%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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cellular senescence

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based on heuristic

inferred from title

5

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1 March 2020

13

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1 March 2020

author name string

Gai Yan

1

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1 March 2020

Mark S Eller

2

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1 March 2020

Courtney Elm

3

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1 March 2020

Cecilia A Larocca

4

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1 March 2020

Izabela P Panova

6

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1 March 2020

Beverley M Dancy

7

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1 March 2020

Erin M Bowers

8

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1 March 2020

David Meyers

9

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1 March 2020

Lisa Lareau

10

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1 March 2020

Philip A Cole

11

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1 March 2020

Sean D Taverna

12

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1 March 2020

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18 April 2013

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1 March 2020

Journal of Investigative Dermatology

1 reference

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1 March 2020

133

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1 March 2020

10

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1 March 2020

2444-2452

1 reference

Europe PubMed Central

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1 March 2020

https://scigraph.springernature.com/pub.10.1038/jid.2013.187

0 references

Molecular Network Associated with MITF in Skin Melanoma Development and Progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Upregulation of Fanconi anemia DNA repair genes in melanoma compared with non-melanoma skin cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Epigenetic modifications as therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Expanded roles of the Fanconi anemia pathway in preserving genomic stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Using ChIP-seq technology to identify targets of zinc finger transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Limitations of MTT and MTS-based assays for measurement of antiproliferative activity of green tea polyphenols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Histone acetyl transferases as emerging drug targets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Roles of the histone acetyltransferase monocytic leukemia zinc finger protein in normal and malignant hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Id1 delays senescence of primary human melanocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Determining cell cycle stages by flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

The NCI60 human tumour cell line anticancer drug screen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

p300/CBP and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Roles of cyclin D1 and related genes in growth inhibition, senescence and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

p300/CBP proteins: HATs for transcriptional bridges and scaffolds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Anticancer drug targets: cell cycle and checkpoint control.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Increased expression of cyclin D2 during multiple states of growth arrest in primary and established cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

The transcriptional coactivators p300 and CBP are histone acetyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Cyclin A is required at two points in the human cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

10 September 2017

Regulation of E2Fs and senescence by PML nuclear bodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

14 September 2017

Modeling genomic diversity and tumor dependency in malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

14 September 2017

Labeling cells in microtiter plates for determination of [3H]thymidine uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

21 August 2018

Cyclin D1 overexpression permits the reproducible detection of senescent human vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

21 August 2018

p300 is required for orderly G1/S transition in human cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

21 August 2018

Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

21 August 2018

Cyclin: a nuclear protein whose level correlates directly with the proliferative state of normal as well as transformed cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380234

21 August 2018

Extraction, purification and analysis of histones

1 reference

https://pubmed.ncbi.nlm.nih.gov/23698071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Point mutations and allelic loss in the TP53 locus of cutaneous malignant melanomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/23698071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CBP/p300 as a co-factor for the Microphthalmia transcription factor

2 references

https://pubmed.ncbi.nlm.nih.gov/23698071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

https://api.crossref.org/works/10.1038%2FJID.2013.187

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/23698071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/JID.2013.187

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698071%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698071%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698071%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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