(Q39161442)

English

Knockdown of DEPTOR inhibits cell proliferation and increases chemosensitivity to melphalan in human multiple myeloma RPMI-8226 cells via inhibiting PI3K/AKT activity

scientific article published on 15 April 2013

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Knockdown of DEPTOR inhibits cell proliferation and increases chemosensitivity to melphalan in human multiple myeloma RPMI-8226 cells via inhibiting PI3K/AKT activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

multiple myeloma

1 reference

based on heuristic

inferred from title

author name string

Hao-Ran Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Jun-Min Chen

2

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Zhi-Yong Zeng

3

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Wen-Zhong Que

4

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

publication date

15 April 2013

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Journal of International Medical Research

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

41

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

584-595

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Multiple myeloma.

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Emerging therapies for the treatment of relapsed or refractory multiple myeloma

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Targets and mechanisms for the regulation of translation in malignant transformation

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

PI3K/Akt/mTOR pathway as a target for cancer therapy

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Exploiting the PI3K/AKT pathway for cancer drug discovery

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagy

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Importin 7 may be dispensable for human immunodeficiency virus type 1 and simian immunodeficiency virus infection of primary macrophages

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Enhanced proliferation of cultured human vascular smooth muscle cells linked to increased function of RNA-binding protein HuR

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Real-time fluorescent quantitative polymerase chain reaction study of polo-like kinase-1 in pterygia

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

High expression levels of the mammalian target of rapamycin inhibitor DEPTOR are predictive of response to thalidomide in myeloma.

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Lenalidomide in combination with melphalan and dexamethasone in patients with newly diagnosed AL amyloidosis: a multicenter phase 1/2 dose-escalation study

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Knockdown of c-Met enhances sensitivity to bortezomib in human multiple myeloma U266 cells via inhibiting Akt/mTOR activity

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

DEPTOR expression and response to thalidomide: toward a new therapeutic target in multiple myeloma?

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

mTOR and cancer: many loops in one pathway.

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

mTORC1 signaling requires proteasomal function and the involvement of CUL4-DDB1 ubiquitin E3 ligase

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation.

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Defining the role of mTOR in cancer

1 reference

https://api.crossref.org/works/10.1177%2F0300060513480920

21 January 2018

Identifiers

10.1177/0300060513480920

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39161442&oldid=1810892972"