(Q39166823)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23584479%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells (English)

1 reference

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28 February 2020

1

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28 February 2020

Giulia Fontemaggi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23584479%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Silvia Di Agostino

3

1 reference

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28 February 2020

Sara Donzelli

4

1 reference

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28 February 2020

author name string

E Carcarino

5

1 reference

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28 February 2020

S Strano

6

1 reference

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28 February 2020

G Blandino

7

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28 February 2020

language of work or name

English

0 references

publication date

15 April 2013

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28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23584479%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

33

1 reference

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28 February 2020

issue

12

1 reference

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28 February 2020

page(s)

1601-1608

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https://scigraph.springernature.com/pub.10.1038/onc.2013.106

28 February 2020

exact match

0 references

cites work

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Blinded by the Light: The Growing Complexity of p53

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Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1.

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Targeting p53 for enhanced radio- and chemo-sensitivity.

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Mutant p53 protein expression interferes with p53-independent apoptotic pathways.

21 January 2018

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Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis

21 January 2018

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Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

21 January 2018

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Mutant p53 forms a complex with Sp1 on HIV-LTR DNA.

21 January 2018

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Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

21 January 2018

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The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.

21 January 2018

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Mutant p53 proteins bind DNA in a DNA structure-selective mode

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Increased microRNA activity in human cancers

21 January 2018

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MicroRNA-mediated breast cancer metastasis: from primary site to distant organs

21 January 2018

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MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function

21 January 2018

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MicroRNA signatures in human cancers

21 January 2018

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An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling.

21 January 2018

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A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.106

Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

21 January 2018

1 reference

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Delta-crystallin enhancer binding factor 1 controls the epithelial to mesenchymal transition phenotype and resistance to the epidermal growth factor receptor inhibitor erlotinib in human head and neck squamous cell carcinoma lines

21 January 2018

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Development and characterization of gemcitabine-resistant pancreatic tumor cells.

21 January 2018

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Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.

21 January 2018

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The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiation

21 January 2018

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Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.

21 January 2018

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Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

21 January 2018

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Potential role of miR-9 and miR-223 in recurrent ovarian cancer

21 January 2018

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Micro-RNA profiling in kidney and bladder cancers

21 January 2018

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MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1.

21 January 2018

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MiR-223 suppresses cell proliferation by targeting IGF-1R.

21 January 2018

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The role of stathmin in the regulation of the cell cycle

21 January 2018

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Role for protein phosphatases in the cell-cycle-regulated phosphorylation of stathmin

21 January 2018

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Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors

21 January 2018

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Identification of novel nasopharyngeal carcinoma biomarkers by laser capture microdissection and proteomic analysis

21 January 2018

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Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation

21 January 2018

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Stathmin, a new target of PRL-3 identified by proteomic methods, plays a key role in progression and metastasis of colorectal cancer

21 January 2018

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Stathmin: a protein with many tasks. New biomarker and potential target in cancer

21 January 2018

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In vivo safety and antitumor efficacy of bifunctional small hairpin RNAs specific for the human Stathmin 1 oncoprotein.

21 January 2018

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Stathmin 1: a novel therapeutic target for anticancer activity

21 January 2018

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Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction.

21 January 2018

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

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Silencing of stathmin induces tumor-suppressor function in breast cancer cell lines harboring mutant p53.

21 January 2018

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Protumorigenic overexpression of stathmin/Op18 by gain-of-function mutation in p53 in human hepatocarcinogenesis.

21 January 2018

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Stathmin1 plays oncogenic role and is a target of microRNA-223 in gastric cancer

21 January 2018

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p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

21 January 2018

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Stathmin interaction with a putative kinase and coiled-coil-forming protein domains

21 January 2018

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Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin

21 January 2018

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Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

21 January 2018

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Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

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When mutants gain new powers: news from the mutant p53 field.

21 January 2018

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Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

31 March 2020

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Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy

31 March 2020

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Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

31 March 2020

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Involvement of OP18 in cell proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.106

p53-mediated negative regulation of stathmin/Op18 expression is associated with G(2)/M cell-cycle arrest

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.106

The prognostic value of Stathmin-1, S100A2, and SYK proteins in ER-positive primary breast cancer patients treated with adjuvant tamoxifen monotherapy: an immunohistochemical study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.106

Stathmin interaction with HSC70 family proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.106

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23584479%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23584479%20AND%20SRC:MED&resulttype=core&format=json