(Q39197452)

9 September 2017

Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatform (English)

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9 September 2017

5

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9 September 2017

Lígia C Gomes-da-Silva

1

1 reference

9 September 2017

Yolanda Fernández

2

1 reference

9 September 2017

Ibane Abasolo

3

1 reference

9 September 2017

Simo Schwartz

4

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9 September 2017

Maria C Pedroso de Lima

6

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9 September 2017

Sérgio Simões

7

1 reference

9 September 2017

João N Moreira

8

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9 September 2017

language of work or name

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8 February 2013

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9 September 2017

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9 September 2017

8

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9 September 2017

9

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9 September 2017

1397-1413

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RNA interference is mediated by 21- and 22-nucleotide RNAs

9 September 2017

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Non-viral lipid-based nanoparticles for targeted cancer systemic gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Knocking down barriers: advances in siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: impact on the treatment of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Design of peptide-targeted liposomes containing nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Characterization of the inhibitory effect of PEG-lipid conjugates on the intracellular delivery of plasmid and antisense DNA mediated by cationic lipid liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Theory of tunable pH-sensitive vesicles of anionic and cationic lipids or anionic and neutral lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Overcoming the innate immune response to small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Neuroblastoma targeting by c-myb-selective antisense oligonucleotides entrapped in anti-GD2 immunoliposome: immune cell-mediated anti-tumor activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

CpG motifs in pDNA-sequences increase anti-PEG IgM production induced by PEG-coated pDNA-lipoplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Immunogenicity and rapid blood clearance of liposomes containing polyethylene glycol-lipid conjugates and nucleic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Targeting Stealth liposomes in a murine model of human small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Use of the post-insertion technique to insert peptide ligands into pre-formed stealth liposomes with retention of binding activity and cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Transferrin receptor-targeted liposomes encapsulating anti-BCR-ABL siRNA or asODN for chronic myeloid leukemia treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Stabilized plasmid-lipid particles for regional gene therapy: formulation and transfection properties

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Aminopeptidase A is a functional target in angiogenic blood vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Off-target effects of siRNA specific for GFP

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

PEGylation of proteins and liposomes: a powerful and flexible strategy to improve the drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

In vitro characterization of a targeted, dye-loaded nanodevice for intraoperative tumor delineation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Vascular targeted nanoparticles for imaging and treatment of brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

F3-targeted cisplatin-hydrogel nanoparticles as an effective therapeutic that targets both murine and human ovarian tumor endothelial cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Insertion of poly(ethylene glycol) derivatized phospholipid into pre-formed liposomes results in prolonged in vivo circulation time

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

The polymorphic phase behaviour of phosphatidylethanolamines of natural and synthetic origin. A 31P NMR study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Sterically stabilized pH-sensitive liposomes. Intracellular delivery of aqueous contents and prolonged circulation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Co-encapsulation of anti-BCR-ABL siRNA and imatinib mesylate in transferrin receptor-targeted sterically stabilized liposomes for chronic myeloid leukemia treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Neuroblastoma-targeted nanoparticles entrapping siRNA specifically knockdown ALK.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Inhibition of influenza virus production in virus-infected mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

Protection against lethal influenza virus challenge by RNA interference in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.174

21 January 2018

Identifiers

DOI

10.2217/NNM.12.174

1 reference

9 September 2017

1 reference