(Q39203621)

10 September 2017

title

Ganglioside GM3 inhibits hepatoma cell motility via down-regulating activity of EGFR and PI3K/AKT signaling pathway (English)

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10 September 2017

main subject

hepatocellular carcinoma

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X Huang

1

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10 September 2017

Y Li

2

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10 September 2017

J Zhang

3

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10 September 2017

Y Xu

4

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10 September 2017

Y Tian

5

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10 September 2017

K Ma

6

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10 September 2017

publication date

1 July 2013

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Journal of Cellular Biochemistry

10 September 2017

published in

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10 September 2017

volume

114

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10 September 2017

issue

7

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10 September 2017

page(s)

1616-1624

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Role of tumor-associated gangliosides in cancer progression

10 September 2017

cites work

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c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

21 January 2018

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The role of the PI3K-AKT pathway in melanoma

21 January 2018

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The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches.

21 January 2018

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Ganglioside GM3 inhibits proliferation and invasion of glioma.

21 January 2018

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Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells

21 January 2018

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Glycosphingolipids in cellular interaction, differentiation, and oncogenesis

21 January 2018

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Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility

21 January 2018

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Physiology and pathophysiology of sphingolipid metabolism and signaling

21 January 2018

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Tetraspanin CD9 is a "proteolipid," and its interaction with alpha 3 integrin in microdomain is promoted by GM3 ganglioside, leading to inhibition of laminin-5-dependent cell motility

21 January 2018

1 reference

A solvent partition method for microscale ganglioside purification.

21 January 2018

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GM3 as a novel growth regulator for human gliomas

21 January 2018

1 reference

GM3 ganglioside inhibits CD9-facilitated haptotactic cell motility: coexpression of GM3 and CD9 is essential in the downregulation of tumor cell motility and malignancy

21 January 2018

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Ganglioside GM3 and its biological functions

21 January 2018

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Ganglioside GM3 inhibition of EGF receptor mediated signal transduction

21 January 2018

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Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains

21 January 2018

1 reference

Growth inhibition of human lung adenocarcinoma cells by antibodies against epidermal growth factor receptor and by ganglioside GM3: involvement of receptor-directed protein tyrosine phosphatase(s).

21 January 2018

1 reference

Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway

21 January 2018

1 reference

Cell growth regulation through GM3-enriched microdomain (glycosynapse) in human lung embryonal fibroblast WI38 and its oncogenic transformant VA13.

21 January 2018

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Ganglioside GM3 blocks the activation of epidermal growth factor receptor induced by integrin at specific tyrosine sites

21 January 2018

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Biological significance of isolated tumor cells and micrometastasis in lymph nodes evaluated using a green fluorescent protein-tagged human gastric cancer cell line.

21 January 2018

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Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor

21 January 2018

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GM3-enriched Microdomain Involved in Cell Adhesion and Signal Transduction through Carbohydrate-Carbohydrate Interaction in Mouse Melanoma B16 Cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCB.24503

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10 September 2017

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