(Q39203663)

10 September 2017

Alternative splicing of BRAF transcripts and characterization of C-terminally truncated B-Raf isoforms in colorectal cancer (English)

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alternative mRNA splicing, via spliceosome

10 September 2017

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1

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10 September 2017

Frank T Kolligs

2

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PubMed ID

23354951

10 September 2017

language of work or name

English

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publication date

27 February 2013

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International Journal of Cancer

10 September 2017

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10 September 2017

133

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10 September 2017

590-596

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10 September 2017

3

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Mutations of the BRAF gene in human cancer

10 September 2017

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The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression.

21 January 2018

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Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf

21 January 2018

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Differential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanisms

21 January 2018

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B-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouse

21 January 2018

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Concomitant mutations and splice variants in KRAS and BRAF demonstrate complex perturbation of the Ras/Raf signalling pathway in advanced colorectal cancer

21 January 2018

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

21 January 2018

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Classification of colorectal cancer based on correlation of clinical, morphological and molecular features

21 January 2018

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Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells

21 January 2018

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Genome signatures of colon carcinoma cell lines

21 January 2018

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Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

21 January 2018

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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

21 January 2018

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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

21 January 2018

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Aberrant BRAF splicing as an alternative mechanism for oncogenic B-Raf activation in thyroid carcinoma.

21 January 2018

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

21 January 2018

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Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays

21 January 2018

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Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay

21 January 2018

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

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21 January 2018

The meaning of nonsense

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Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression

21 January 2018

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Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4

21 January 2018

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Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury

21 January 2018

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Alternative splicing of the murine receptor for advanced glycation end-products (RAGE) gene

21 January 2018

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DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras-ERK pathway, is required for myogenic differentiation

21 January 2018

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c-Myc regulates RNA splicing of the A-Raf kinase and its activation of the ERK pathway

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.28061

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10 September 2017

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PubMed ID

23354951