(Q39208382)

English

Positive feedback loop and synergistic effects between hypoxia-inducible factor-2α and stearoyl-CoA desaturase-1 promote tumorigenesis in clear cell renal cell carcinoma

scientific article published on 3 March 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Positive feedback loop and synergistic effects between hypoxia-inducible factor-2α and stearoyl-CoA desaturase-1 promote tumorigenesis in clear cell renal cell carcinoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

author name string

Yujian Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Hui Wang

2

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Jin Zhang

3

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Jianwei Lv

4

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Yiran Huang

5

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

publication date

3 March 2013

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

104

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

416-422

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Hypoxia signalling in cancer and approaches to enforce tumour regression

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Role of VHL gene mutation in human renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Hypoxia-inducible factors and the response to hypoxic stress

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy.

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Hypoxia-inducible factor 2 regulates hepatic lipid metabolism

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Regulation of stearoyl-CoA desaturase genes: role in cellular metabolism and preadipocyte differentiation

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPK

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Activation of epithelial growth factor receptor pathway by unsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Increase in fluidity in the membrane of MT3 breast cancer cells correlates with enhanced cell adhesion in vitro and increased lung metastasis in NOD/SCID mice

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Hypoxic transcription gene profiles under the modulation of nitric oxide in nuclear run on-microarray and proteomics

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

The fatty acid desaturation index of blood lipids, as a biomarker of hepatic stearoyl-CoA desaturase expression, is a predictive factor of breast cancer risk

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Functional distinctions of protein kinase B/Akt isoforms defined by their influence on cell migration

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element.

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12108

21 January 2018

Oleate activates phosphatidylinositol 3-kinase and promotes proliferation and reduces apoptosis of MDA-MB-231 breast cancer cells, whereas palmitate has opposite effects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23331615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23331615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feedback regulators of hypoxia-inducible factors and their role in cancer biology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23331615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23331615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of human delta-6-desaturase is associated with aggressiveness of human breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23331615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Stearoyl-CoA Desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23331615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23331615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/CAS.12108

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

ResearchGate publication ID

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