(Q39225627)

10 September 2017

title

Mutant p53 binds to estrogen receptor negative promoter via DNMT1 and HDAC1 in MDA-MB-468 breast cancer cells (English)

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10 September 2017

Rita Arabsolghar

1

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10 September 2017

Tayebeh Azimi

series ordinal

2

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10 September 2017

Mozhgan Rasti

series ordinal

3

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10 September 2017

publication date

15 December 2012

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Molecular Biology Reports

10 September 2017

published in

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10 September 2017

volume

40

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10 September 2017

issue

3

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10 September 2017

page(s)

2617-2625

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https://scigraph.springernature.com/pub.10.1007/s11033-012-2348-7

10 September 2017

exact match

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cites work

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Release of methyl CpG binding proteins and histone deacetylase 1 from the Estrogen receptor alpha (ER) promoter upon reactivation in ER-negative human breast cancer cells

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Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines.

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A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine.

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Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

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Regulation of DNA methyltransferase 1 by interactions and modifications

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Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1

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Regulation of estrogen receptor-alpha expression by the tumor suppressor gene p53 in MCF-7 cells

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KLF4 suppresses estrogen-dependent breast cancer growth by inhibiting the transcriptional activity of ERalpha

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Transcriptional regulation of estrogen receptor-alpha by p53 in human breast cancer cells

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RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells

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21 January 2018

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Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters

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Histone deacetylases specifically down-regulate p53-dependent gene activation

21 January 2018

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DNA damage-induced down-regulation of human Cdc25C and Cdc2 is mediated by cooperation between p53 and maintenance DNA (cytosine-5) methyltransferase 1.

21 January 2018

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Promoter methylation of O(6)-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53.

21 January 2018

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Mutant p53 mediates survival of breast cancer cells

21 January 2018

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One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-012-2348-7

Transcriptional activation of estrogen receptor alpha in human breast cancer cells by histone deacetylase inhibition

21 January 2018

1 reference

12 December 2020

Mapping of ER gene CpG island methylation-specific polymerase chain reaction.

1 reference

12 December 2020

p53 Binds to estrogen receptor 1 promoter in human breast cancer cells

1 reference

12 December 2020

Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression.

1 reference

12 December 2020

Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing CCN5/WISP-2

1 reference

12 December 2020

Epigenetic Reactivation of Estrogen Receptor: Promising Tools for Restoring Response to Endocrine Therapy.

1 reference

12 December 2020

Association between HIC1 and RASSF1A promoter hypermethylation with MTHFD1 G1958A polymorphism and clinicopathological features of breast cancer in Iranian patients.

1 reference

12 December 2020

Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.

1 reference

12 December 2020

10.1007/S11033-012-2348-7

Identifiers

DOI

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release_umuegvzsa5gy7hkyjsdmgymdji

10 September 2017

Fatcat ID

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1 reference