(Q39246185)

10 September 2017

A systematic screen reveals MicroRNA clusters that significantly regulate four major signaling pathways (English)

1 reference

10 September 2017

1 reference

Lindsey E Becker

1

1 reference

10 September 2017

Zhongxin Lu

2

1 reference

10 September 2017

Weiqun Chen

3

1 reference

10 September 2017

Wei Xiong

4

1 reference

10 September 2017

Maiying Kong

5

1 reference

10 September 2017

Yong Li

6

1 reference

10 September 2017

language of work or name

English

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publication date

8 November 2012

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10 September 2017

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10 September 2017

7

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10 September 2017

11

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10 September 2017

e48474

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Creative Commons Attribution 4.0 International

10 September 2017

start time

8 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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MicroRNAs miR-125a and miR-125b constitutively activate the NF-κB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)

10 September 2017

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MYC on the path to cancer

10 September 2017

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miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death.

10 September 2017

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The diverse and complex roles of NF-κB subunits in cancer

10 September 2017

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MicroRNAs coordinately regulate protein complexes

10 September 2017

1 reference

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Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

10 September 2017

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Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis.

10 September 2017

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Apoptosis and the target genes of microRNA-21.

10 September 2017

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MicroRNAs in NF-kappaB signaling

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

MicroRNA history: discovery, recent applications, and next frontiers.

10 September 2017

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Hallmarks of Cancer: The Next Generation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

miR-301a as an NF-κB activator in pancreatic cancer cells

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Negative regulation of the tumor suppressor p53 gene by microRNAs.

10 September 2017

1 reference

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Regulation of Myc by miR-34c: A mechanism to prevent genomic instability?

10 September 2017

1 reference

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MicroRNA-21 in cardiovascular disease

10 September 2017

1 reference

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miR-200 de-FOGs insulin signaling.

10 September 2017

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AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

The p53 Pathway Encounters the MicroRNA World

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

miR-200 enhances mouse breast cancer cell colonization to form distant metastases

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Clustered microRNAs' coordination in regulating protein-protein interaction network

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Intrauterine growth restriction, human placental development and trophoblast cell death

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Blinded by the Light: The Growing Complexity of p53

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Translational regulation mechanisms of AP-1 proteins

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Reflecting on 25 years with MYC.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Control of cell proliferation pathways by microRNAs

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

A computational screen for mouse signaling pathways targeted by microRNA clusters.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Rewired ERK-JNK signaling pathways in melanoma

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Processing of intronic microRNAs

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

miRGen: a database for the study of animal microRNA genomic organization and function

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Principles of microRNA regulation of a human cellular signaling network

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Nuclear factor-kappaB in cancer development and progression

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Complex networks orchestrate epithelial-mesenchymal transitions

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

AP-1 subunits: quarrel and harmony among siblings

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

MicroRNAs: genomics, biogenesis, mechanism, and function

10 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

10 September 2017

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048474

Post-translational modifications and activation of p53 by genotoxic stresses

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

c-Myc target genes involved in cell growth, apoptosis, and metabolism

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

10 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

10 September 2017

https://pubmed.ncbi.nlm.nih.gov/23144891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MicroRNA-200b regulates cell proliferation, invasion, and migration by directly targeting ZEB2 in gastric carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

p53 expression overcomes p21WAF1/CIP1-mediated G1 arrest and induces apoptosis in human cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

MicroRNA-10a is overexpressed in human pancreatic cancer and involved in its invasiveness partially via suppression of the HOXA1 gene.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493556

Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23144891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23144891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0048474

1 reference

10 September 2017

0 references

1 reference

10 September 2017

PubMed publication ID

23144891

1 reference