(Q39248972)

10 September 2017

Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway (English)

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10 September 2017

neoplastic stem cells

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1 reference

Shih-Hui Li

1

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10 September 2017

Junsheng Fu

2

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10 September 2017

Dara Nall Watkins

3

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10 September 2017

Rakesh K Srivastava

4

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10 September 2017

Sharmila Shankar

5

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10 September 2017

6 November 2012

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Molecular and Cellular Biochemistry

10 September 2017

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10 September 2017

373

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10 September 2017

1-2

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10 September 2017

217-227

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https://scigraph.springernature.com/pub.10.1007/s11010-012-1493-6

10 September 2017

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cites work

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

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Development and characterization of gemcitabine-resistant pancreatic tumor cells.

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Pancreatic cancer stem cells--insights and perspectives

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Stem cells, cancer, and cancer stem cells

21 January 2018

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Self-renewal and solid tumor stem cells

21 January 2018

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Pancreatic cancer stem cells: new understanding of tumorigenesis, clinical implications

21 January 2018

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

21 January 2018

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Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

21 January 2018

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Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: it's inhibition leads to growth suppression and apoptosis

21 January 2018

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Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

21 January 2018

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

21 January 2018

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Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathway

21 January 2018

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Multi-targeted prevention of cancer by sulforaphane

21 January 2018

1 reference

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Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion.

21 January 2018

1 reference

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Modulation of markers associated with aggressive phenotype in MDA-MB-231 breast carcinoma cells by sulforaphane

21 January 2018

1 reference

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Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Cruciferous vegetable intake is inversely associated with lung cancer risk among smokers: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Breast cancer cell growth inhibition by phenethyl isothiocyanate is associated with down-regulation of oestrogen receptor-alpha36

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Sulforaphane inhibits constitutive and interleukin-6-induced activation of signal transducer and activator of transcription 3 in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Efficacy of sulforaphane in eradicating Helicobacter pylori in human gastric xenografts implanted in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells

21 January 2018

1 reference

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Chemopreventive agent sulforaphane enhances radiosensitivity in human tumor cells.

21 January 2018

1 reference

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Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics

21 January 2018

1 reference

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Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms

21 January 2018

1 reference

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Sonic hedgehog signaling inhibition provides opportunities for targeted therapy by sulforaphane in regulating pancreatic cancer stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Sulforaphane potentiates the efficacy of 17-allylamino 17-demethoxygeldanamycin against pancreatic cancer through enhanced abrogation of Hsp90 chaperone function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Sulforaphane increases drug-mediated cytotoxicity toward cancer stem-like cells of pancreas and prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

21 January 2018

1 reference

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Epithelial-mesenchymal transition in cancer development and its clinical significance

21 January 2018

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Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins

21 January 2018

1 reference

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miR-200b regulates cell migration via Zeb family during mouse palate development.

21 January 2018

1 reference

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ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Zeb1 links epithelial-mesenchymal transition and cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Intrinsic chemoresistance to gemcitabine is associated with decreased expression of BNIP3 in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Pancreatic cancer stem cells and relevance to cancer treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Hedgehog signaling in pancreas development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

GLI transcription factors: mediators of oncogenic Hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Botanicals in cancer chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-012-1493-6

21 January 2018

1 reference

12 December 2020

Pancreatic cancer stem cells and EMT in drug resistance and metastasis.

1 reference

12 December 2020

Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review).

1 reference

12 December 2020

Absolute bioavailability and dose-dependent pharmacokinetic behaviour of dietary doses of the chemopreventive isothiocyanate sulforaphane in rat

1 reference

12 December 2020

Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review).

1 reference

12 December 2020

Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells

1 reference

12 December 2020

Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.

1 reference

12 December 2020

Pancreatic cancer cells resistant to chemoradiotherapy rich in "stem-cell-like" tumor cells

1 reference

12 December 2020

10.1007/S11010-012-1493-6

Identifiers

DOI

1 reference

10 September 2017

1 reference