(Q39253159)

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Quercetin and its major metabolites selectively modulate cyclic GMP-dependent relaxations and associated tolerance in pig isolated coronary artery

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scholarly article

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16 January 2020

Quercetin and its major metabolites selectively modulate cyclic GMP-dependent relaxations and associated tolerance in pig isolated coronary artery (English)

1 reference

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16 January 2020

3

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16 January 2020

5

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16 January 2020

7

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16 January 2020

author name string

S Suri

1

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16 January 2020

X H Liu

2

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16 January 2020

D A Hughes

4

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16 January 2020

P W Needs

6

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16 January 2020

S Tribolo

8

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16 January 2020

V G Wilson

9

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16 January 2020

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publication date

24 December 2009

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16 January 2020

British Journal of Pharmacology

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16 January 2020

159

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16 January 2020

3

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16 January 2020

566-575

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16 January 2020

Role of cGMP-dependent protein kinase in development of tolerance to nitroglycerine in porcine coronary arteries

1 reference

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Failure of vitamin E in clinical trials: is gamma-tocopherol the answer?

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10 September 2017

In vitro biological properties of flavonoid conjugates found in vivo.

1 reference

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10 September 2017

Polyphenols and cardiovascular disease: effects on endothelial and platelet function

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Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies

1 reference

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10 September 2017

Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships

1 reference

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10 September 2017

How should we assess the effects of exposure to dietary polyphenols in vitro?

1 reference

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Nitric oxide as a unique signaling molecule in the vascular system: a historical overview

1 reference

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10 September 2017

Nitrate tolerance: a unifying hypothesis

1 reference

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10 September 2017

Enzymatic activation of endothelial protease-activated receptors is dependent on artery diameter in human and porcine isolated coronary arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

10 September 2017

Quercetin as a novel activator of L-type Ca(2+) channels in rat tail artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

10 September 2017

The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

1 reference

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10 September 2017

Mechanisms of L-NG nitroarginine/indomethacin-resistant relaxation in bovine and porcine coronary arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

10 September 2017

Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

10 September 2017

Flavonoid intake and coronary mortality in Finland: a cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

10 September 2017

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

10 September 2017

Pharmacological reactivity of human epicardial coronary arteries: characterization of relaxation responses to endothelium-derived relaxing factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

10 September 2017

Organic nitrate esters: clinical use and mechanisms of actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

10 September 2017

Macrophage as a target of quercetin glucuronides in human atherosclerotic arteries: implication in the anti-atherosclerotic mechanism of dietary flavonoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

14 September 2017

Cyclic nucleotide phosphodiesterases and vascular smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

25 September 2017

Vasorelaxation and inhibition of the voltage-operated Ca2+ channels by FK506 in the porcine coronary artery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

17 June 2018

Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNF alpha generation from human monocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

17 June 2018

Tolerance to sodium nitroprusside. Studies in cultured porcine vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

17 June 2018

Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

17 June 2018

Mechanisms of vasodilation induced by NKH477, a water-soluble forskolin derivative, in smooth muscle of the porcine coronary artery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

17 June 2018

Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Prevention of nitroglycerin tolerance in vitro by T0156, a selective phosphodiesterase type 5 inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: lack of association between antioxidant and lipoxygenase inhibitory activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Effect of resveratrol on nitrate tolerance in isolated human internal mammary artery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Inhibition of phosphodiesterase 5 selectively reverses nitrate tolerance in the venous circulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Liquid chromatography-tandem mass spectroscopy assay for quercetin and conjugated quercetin metabolites in human plasma and urine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Genistein reduces agonist-induced contractions of porcine coronary arterial smooth muscle in a cyclic AMP-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Nitric oxide (NO) scavenging and NO protecting effects of quercetin and their biological significance in vascular smooth muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Differential effects of quercetin, a natural polyphenolic flavonoid, on L-type calcium current in pituitary tumor (GH3) cells and neuronal NG108-15 cells

1 reference

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21 August 2018

Effects of quercetin and rutin on vascular preparations: a comparison between mechanical and electrophysiological phenomena

1 reference

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21 August 2018

Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries

1 reference

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21 August 2018

Involvement of nitric oxide, cyclic GMP and phosphodiesterase 5 in excitatory amino acid and GABA release in the nucleus accumbens evoked by activation of the hippocampal fimbria

1 reference

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21 August 2018

Interactions of sildenafil with various coronary vasodilators in isolated porcine coronary artery

1 reference

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21 August 2018

Endothelin-1 synthesis reduced by red wine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

KCl depolarization increases Ca2+ sensitivity of contractile elements in coronary arterial smooth muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828021

21 August 2018

Endothelium-dependent vasorelaxing activity of wine and other grape products

1 reference

https://pubmed.ncbi.nlm.nih.gov/20050852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vasodilator effects of quercetin in isolated rat vascular smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20050852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relaxation to flavones and flavonols in rat isolated thoracic aorta: mechanism of action and structure-activity relationships

1 reference

https://pubmed.ncbi.nlm.nih.gov/20050852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of red and white wine on endothelium-dependent vasorelaxation of rat aorta and human coronary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/20050852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kaempferol enhances endothelium-independent and dependent relaxation in the porcine coronary artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/20050852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2009.00556.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20050852%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20050852%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20050852%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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