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Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance.
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3607219
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10 March 2020
title
Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance
(English)
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10 March 2020
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Michelle D Leach
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2
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10 March 2020
Leah E Cowen
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10 March 2020
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Nicole Robbins
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publication date
4 October 2012
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Cell Reports
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2
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4
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10 March 2020
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878-888
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cites work
Exploring the yeast acetylome using functional genomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Phase I-II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat-induced tubulin acetylation and Hsp90 inhibition in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Candida albicans morphogenesis and host defence: discriminating invasion from colonization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Hsp90 governs dispersion and drug resistance of fungal biofilms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Regulatory circuitry governing fungal development, drug resistance, and disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Hsp90 and environmental stress transform the adaptive value of natural genetic variation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
An insight into the antifungal pipeline: selected new molecules and beyond.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Targeting the dynamic HSP90 complex in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Epidemiology of invasive mycoses in North America
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Lysine acetylation targets protein complexes and co-regulates major cellular functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Histone deacetylase inhibitors: molecular mechanisms of action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Functions of site-specific histone acetylation and deacetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
An acetylation site in the middle domain of Hsp90 regulates chaperone function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Genetic architecture of Hsp90-dependent drug resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Anticancer activities of histone deacetylase inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Biochemical and genetic analysis of the yeast proteome with a movable ORF collection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Role of molecular chaperones in steroid receptor action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
A statistical model for identifying proteins by tandem mass spectrometry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Global analysis of protein expression in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Mode of Selection and Experimental Evolution of Antifungal Drug Resistance in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Functional profiling of the Saccharomyces cerevisiae genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Histone deacetylases and cancer: causes and therapies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Isogenic strain construction and gene mapping in Candida albicans.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
10 September 2017
Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
14 September 2017
The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14alpha demethylase in Candida albicans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
14 September 2017
HDACs link the DNA damage response, processing of double-strand breaks and autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
15 June 2018
Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
15 June 2018
Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
15 June 2018
Mammalian glucocorticoid receptor derivatives enhance transcription in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
15 June 2018
Metabolic control of antifungal drug resistance.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
21 August 2018
CRZ1, a target of the calcineurin pathway in Candida albicans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
21 August 2018
Modulating molecular chaperone Hsp90 functions through reversible acetylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
21 August 2018
Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607219
retrieved
21 August 2018
Isolation and partial characterization of Hsp90 from Candida albicans
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23041319
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Stable azole drug resistance associated with a substrain of Candida albicans from an HIV-infected patient
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23041319
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELREP.2012.08.035
1 reference
stated in
Europe PubMed Central
PMCID
3607219
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23041319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 March 2020
PMCID
3607219
1 reference
stated in
Europe PubMed Central
PMCID
3607219
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23041319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 March 2020
PubMed ID
23041319
1 reference
stated in
Europe PubMed Central
PMCID
3607219
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23041319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 March 2020
ResearchGate publication ID
232065650
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