(Q39265572)

10 September 2017

title

Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex (English)

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10 September 2017

Zhijian Duan

1

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10 September 2017

June X Zou

2

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10 September 2017

Ping Yang

3

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10 September 2017

Yuzhuo Wang

4

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10 September 2017

Alexander D Borowsky

5

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10 September 2017

Allen C Gao

6

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10 September 2017

Hong-Wu Chen

7

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10 September 2017

publication date

4 October 2012

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10 September 2017

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10 September 2017

volume

73

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10 September 2017

issue

5

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10 September 2017

page(s)

455-466

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Molecular genetics of prostate cancer: new prospects for old challenges

10 September 2017

cites work

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Genetic ablation of the amplified-in-breast cancer 1 inhibits spontaneous prostate cancer progression in mice

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Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer

21 January 2018

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ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification

21 January 2018

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Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark

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Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers

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ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

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The polycomb group protein EZH2 is involved in progression of prostate cancer

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Aberrations of EZH2 in cancer

21 January 2018

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

21 January 2018

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Repression of E-cadherin by the polycomb group protein EZH2 in cancer

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EZH2-mediated concordant repression of Wnt antagonists promotes β-catenin-dependent hepatocarcinogenesis.

21 January 2018

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pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

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CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells

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Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis.

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ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer

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Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells

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Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

21 January 2018

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Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor

21 January 2018

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Multiplexed quantum dot labeling of activated c-Met signaling in castration-resistant human prostate cancer

21 January 2018

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Cell differentiation lineage in the prostate

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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E2F activity is biphasically regulated by androgens in LNCaP cells

21 January 2018

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EZH2 promotes proliferation and invasiveness of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

Does prostate cancer co-opt the developmental program?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development

21 January 2018

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https://api.crossref.org/works/10.1002%2FPROS.22587

Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor

21 January 2018

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https://api.crossref.org/works/10.1002%2FPROS.22587

Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1002%2FPROS.22587

Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal

21 January 2018

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Cell-autonomous intracellular androgen receptor signaling drives the growth of human prostate cancer initiating cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FPROS.22587

Polycomb/Trithorax response elements and epigenetic memory of cell identity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

Involvement of p27Kip1 in G1 arrest by high dose 5 alpha-dihydrotestosterone in LNCaP human prostate cancer cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FPROS.22587

Bipolar androgen therapy: the rationale for rapid cycling of supraphysiologic androgen/ablation in men with castration resistant prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

Androgens suppress EZH2 expression via retinoblastoma (RB) and p130-dependent pathways: a potential mechanism of androgen-refractory progression of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

Progress in the discovery of small-molecule inhibitors of bromodomain--histone interactions

21 January 2018

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21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22587

21 January 2018

Identifiers

DOI

10.1002/PROS.22587

1 reference

10 September 2017

1 reference