(Q39278452)

10 September 2017

Overcoming obstacles to developing new analgesics (English)

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10 September 2017

Clifford J Woolf

1

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PubMed ID

20948534

10 September 2017

language of work or name

English

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publication date

14 October 2010

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10 September 2017

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10 September 2017

16

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10 September 2017

1241-1247

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10 September 2017

11

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https://scigraph.springernature.com/pub.10.1038/nm.2230

10 September 2017

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cites work

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Research design considerations for confirmatory chronic pain clinical trials: IMMPACT recommendations

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Diffuse optical tomography activation in the somatosensory cortex: specific activation by painful vs. non-painful thermal stimuli

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Neuronal plasticity: increasing the gain in pain

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An evidence-based algorithm for the treatment of neuropathic pain

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12 December 2020

A novel tool for the assessment of pain: validation in low back pain

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Neuropathic pain: a maladaptive response of the nervous system to damage

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Pharmacology and treatment of neuropathic pains

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A prefrontal non-opioid mechanism in placebo analgesia

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Predicting value of pain and analgesia: nucleus accumbens response to noxious stimuli changes in the presence of chronic pain.

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Cellular and Molecular Mechanisms of Pain

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Pregabalin in fibromyalgia: meta-analysis of efficacy and safety from company clinical trial reports

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Contributions of different modes of TRPV1 activation to TRPV1 antagonist-induced hyperthermia

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12 December 2020

The anti-allodynic alpha(2)delta ligand pregabalin inhibits the trafficking of the calcium channel alpha(2)delta-1 subunit to presynaptic terminals in vivo

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12 December 2020

Why most published research findings are false

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12 December 2020

The placebo response: neurobiological and clinical issues of neurological relevance

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12 December 2020

Pathophysiology of fibromyalgia

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12 December 2020

Integrating nine prescription opioid analgesics and/or four signal detection systems to summarize statewide prescription drug abuse in the United States in 2007.

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12 December 2020

Predictive validity of animal pain models? A comparison of the pharmacokinetic-pharmacodynamic relationship for pain drugs in rats and humans

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12 December 2020

Comparative efficacy and harms of duloxetine, milnacipran, and pregabalin in fibromyalgia syndrome

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12 December 2020

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

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12 December 2020

Case histories in pharmaceutical risk management

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12 December 2020

EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision

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12 December 2020

Progress in genetic studies of pain and analgesia

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12 December 2020

Pain perception is altered by a nucleotide polymorphism in SCN9A

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12 December 2020

Polymorphisms in the GTP cyclohydrolase gene (GCH1) are associated with ratings of capsaicin pain

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12 December 2020

Genetic approaches to functional gastrointestinal disorders

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12 December 2020

Placebo conditioning and placebo analgesia modulate a common brain network during pain anticipation and perception.

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12 December 2020

How Neuroimaging Studies Have Challenged Us to Rethink: Is Chronic Pain a Disease?

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12 December 2020

Time to onset of neuropathic pain reduction: A retrospective analysis of data from nine controlled trials of pregabalin for painful diabetic peripheral neuropathy and postherpetic neuralgia

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12 December 2020

The promotion and marketing of oxycontin: commercial triumph, public health tragedy.

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12 December 2020

Advances in the pathophysiology of tension-type headache: from stress to central sensitization

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12 December 2020

Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations

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12 December 2020

Animal models of pain: progress and challenges

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12 December 2020

NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders.

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12 December 2020

A GTP cyclohydrolase 1 genetic variant delays cancer pain

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12 December 2020

Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity.

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12 December 2020

Current challenges in glia-pain biology

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12 December 2020

Familial pain syndromes from mutations of the NaV1.7 sodium channel

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12 December 2020

Current evidence for a modulation of low back pain by human genetic variants

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12 December 2020

ACTION on the prevention of chronic pain after surgery: public-private partnerships, the future of analgesic drug development

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12 December 2020

Interpreting the clinical importance of group differences in chronic pain clinical trials: IMMPACT recommendations

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12 December 2020

Pregabalin for acute and chronic pain in adults

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12 December 2020

Central sensitization: a generator of pain hypersensitivity by central neural plasticity

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12 December 2020

Emotion recollected in tranquility: lessons learned from the COX-2 saga.

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12 December 2020

Direct evidence for spinal cord involvement in placebo analgesia

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12 December 2020

Understanding fibromyalgia: lessons from the broader pain research community

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12 December 2020

An SCN9A channelopathy causes congenital inability to experience pain

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12 December 2020

Persistent postsurgical pain: risk factors and prevention

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12 December 2020

Sodium channels in normal and pathological pain

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12 December 2020

Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers

1 reference

12 December 2020

Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort

1 reference

12 December 2020

OxyContin abuse and overdose

1 reference

12 December 2020

Future treatment strategies for neuropathic pain.

1 reference

12 December 2020

Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate

1 reference

12 December 2020

The development of new analgesics over the past 50 years: a lack of real breakthrough drugs

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.2230

1 reference

PubMed ID

20948534

Dimensions Publication ID

10 September 2017

0 references

1 reference

PubMed ID

20948534