(Q39283204)

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The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis.

scientific article published on 5 September 2012

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Europe PubMed Central

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12 February 2020

The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis (English)

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12 February 2020

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Stuart Knechtle

8

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12 February 2020

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Nitika A Gupta

1

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12 February 2020

Vasantha L Kolachala

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12 February 2020

Rong Jiang

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12 February 2020

Carlos Abramowsky

4

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12 February 2020

Rene Romero

5

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12 February 2020

Nimita Fifadara

6

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12 February 2020

Frank Anania

7

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12 February 2020

Allan Kirk

9

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12 February 2020

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5 September 2012

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12 February 2020

The American Journal of Pathology

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12 February 2020

181

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12 February 2020

5

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12 February 2020

1693-1701

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12 February 2020

The effect of endogenously released glucose, insulin, glucagon-like peptide 1, ghrelin on cardiac output, heart rate, stroke volume, and blood pressure

1 reference

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17 June 2018

Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice.

1 reference

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17 June 2018

Effects of DPP-4 inhibitors on the heart in a rat model of uremic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Glucagon and a glucagon-GLP-1 dual-agonist increases cardiac performance with different metabolic effects in insulin-resistant hearts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Brain GLP-1 signaling regulates femoral artery blood flow and insulin sensitivity through hypothalamic PKC-δ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Non-alcoholic fatty liver disease: a massive problem.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Hepatocyte apoptosis is enhanced after ischemia/reperfusion in the steatotic liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Quantification of hormone sensitive lipase phosphorylation and colocalization with lipid droplets in murine 3T3L1 and human subcutaneous adipocytes via automated digital microscopy and high-content analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Lipid droplets finally get a little R-E-S-P-E-C-T.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Functional interaction of hormone-sensitive lipase and perilipin in lipolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Perilipin A and the control of triacylglycerol metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Exendin-4, a glucagon-like peptide 1 receptor agonist, protects cholangiocytes from apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Steatosis as a risk factor in liver surgery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Lymphocytic infiltration and immune activation in metallothionein promoter-exendin-4 (MT-Exendin) transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Lipid droplets: a unified view of a dynamic organelle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

The phosphorylation of serine 492 of perilipin a directs lipid droplet fragmentation and dispersion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Role of PAT proteins in lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

The central role of perilipin a in lipid metabolism and adipocyte lipolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Fatty acid synthase blockade protects steatotic livers from warm ischemia reperfusion injury and transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Apoptosis and necrosis in liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Biological actions and therapeutic potential of the glucagon-like peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Fatty liver in liver transplantation and surgery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Single-center analysis of the first 40 adult-to-adult living donor liver transplants using the right lobe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Glucagon-like peptide-I and the control of insulin secretion in the normal state and in NIDDM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

17 June 2018

Oxidative stress and steatosis are cofactors of liver injury in primary biliary cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

21 August 2018

Obesity-induced hepatic hypoperfusion primes for hepatic dysfunction after resuscitated hemorrhagic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

21 August 2018

Steatosis predicts postoperative morbidity following hepatic resection for colorectal metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

21 August 2018

Mouse livers with macrosteatosis are more susceptible to normothermic ischemic injury than those with microsteatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

21 August 2018

Cell signalling of glucagon-like peptide-1 action in rat skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

21 August 2018

Failure of regeneration of the steatotic rat liver: disruption at two different levels in the regeneration pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

21 August 2018

Expression of the glucagon-like peptide-1 receptor gene in rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5691335

21 August 2018

SnapShot: Lipid Droplets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22960075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and proliferation of intrahepatic bile duct after ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22960075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic steatosis and transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22960075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic syndrome and liver transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22960075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of different types of cell death after normothermic liver ischemia-reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22960075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Apoptosis--universal mechanisms of cell death and survival in ischemia and reperfusion: ways to pharmacological control]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22960075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial ischaemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22960075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-grade microsteatosis and delay in hepatic function after orthotopic liver transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22960075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of Donor Fatty Livers for Liver Transplantation. Transplantation 2001; 71: 1221

1 reference

https://pubmed.ncbi.nlm.nih.gov/22960075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.AJPATH.2012.07.015

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960075%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960075%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960075%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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