(Q39290128)

10 September 2017

title

Metronomic chemotherapy with low-dose cyclophosphamide plus gemcitabine can induce anti-tumor T cell immunity in vivo (English)

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10 September 2017

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Miki Tongu

1

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10 September 2017

Nanae Harashima

2

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10 September 2017

Hiroyuki Monma

3

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10 September 2017

Touko Inao

4

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10 September 2017

Takaya Yamada

5

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10 September 2017

Hideyuki Kawauchi

6

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10 September 2017

Mamoru Harada

7

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10 September 2017

publication date

25 August 2012

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Cancer Immunology, Immunotherapy

10 September 2017

published in

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10 September 2017

volume

62

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10 September 2017

issue

2

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10 September 2017

page(s)

383-391

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https://scigraph.springernature.com/pub.10.1007/s00262-012-1343-0

10 September 2017

exact match

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cites work

Regulatory T cells in immune surveillance and treatment of cancer.

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Myeloid-derived suppressor cells: linking inflammation and cancer

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 January 2018

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Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

21 January 2018

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Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.

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Regulatory T cell-resistant CD8+ T cells induced by glucocorticoid-induced tumor necrosis factor receptor signaling.

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Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

21 January 2018

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COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function

21 January 2018

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Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells

21 January 2018

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Calreticulin exposure dictates the immunogenicity of cancer cell death

21 January 2018

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Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

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Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

21 January 2018

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Immunogenic cancer cell death: a key-lock paradigm

21 January 2018

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Immunostimulatory effects of low-dose cyclophosphamide are controlled by inducible nitric oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1343-0

Cyclophosphamide augments antitumor immunity: studies in an autochthonous prostate cancer model

21 January 2018

1 reference

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CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative

21 January 2018

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CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer

21 January 2018

1 reference

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Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity

21 January 2018

1 reference

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Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice

21 January 2018

1 reference

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Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression

21 January 2018

1 reference

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Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1343-0

Low-dose metronomic oral dosing of a prodrug of gemcitabine (LY2334737) causes antitumor effects in the absence of inhibition of systemic vasculogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1343-0

The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1343-0

Intrathymic clonal deletion of V beta 6+ T cells in cyclophosphamide-induced tolerance to H-2-compatible, Mls-disparate antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1343-0

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1343-0

Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1343-0

Subsets of myeloid-derived suppressor cells in tumor-bearing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1343-0

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1343-0

10.1007/S00262-012-1343-0

21 January 2018

Identifiers

DOI

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10 September 2017

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