(Q39297464)

English

The platelet P2Y(12) receptor under normal and pathological conditions. Assessment with the radiolabeled selective antagonist [(3)H]PSB-0413.

scientific article published on 15 August 2012

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scholarly article

1 reference

Europe PubMed Central

10 September 2017

The platelet P2Y(12) receptor under normal and pathological conditions. Assessment with the radiolabeled selective antagonist [(3)H]PSB-0413. (English)

1 reference

Europe PubMed Central

10 September 2017

Christa E Müller

4

1 reference

Europe PubMed Central

10 September 2017

author name string

Philippe Ohlmann

1

1 reference

Europe PubMed Central

10 September 2017

Anna Lecchi

2

1 reference

Europe PubMed Central

10 September 2017

Ali El-Tayeb

3

1 reference

Europe PubMed Central

10 September 2017

Marco Cattaneo

5

1 reference

Europe PubMed Central

10 September 2017

Christian Gachet

6

1 reference

Europe PubMed Central

10 September 2017

publication date

15 August 2012

1 reference

Europe PubMed Central

10 September 2017

Purinergic Signalling

1 reference

Europe PubMed Central

10 September 2017

9

1 reference

Europe PubMed Central

10 September 2017

1

1 reference

Europe PubMed Central

10 September 2017

59-66

1 reference

Europe PubMed Central

10 September 2017

https://scigraph.springernature.com/pub.10.1007/s11302-012-9329-0

0 references

An intact PDZ motif is essential for correct P2Y12 purinoceptor traffic in human platelets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Molecular defects of the platelet P2 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

The platelet P2Y₁₂ receptor for adenosine diphosphate: congenital and drug-induced defects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Quantification of recombinant and platelet P2Y(1) receptors utilizing a [(125)I]-labeled high-affinity antagonist 2-iodo-N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([(125)I]MRS2500)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

P2Y nucleotide receptors: promise of therapeutic applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

New P2Y(12) inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

P2Y12 polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Physiology and pathophysiology of purinergic neurotransmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Regulation of platelet functions by P2 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

[32P]2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([32P]MRS2500), a novel radioligand for quantification of native P2Y1 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

10 September 2017

Distinct clathrin-coated pits sort different G protein-coupled receptor cargo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

14 September 2017

P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

14 September 2017

Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

14 September 2017

Adenine triphosphate nucleotides are antagonists at the P2Y receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

14 September 2017

2-Methylthioadenosine[beta-32P]diphosphate. An agonist and radioligand for the receptor that inhibits the accumulation of cyclic AMP in intact blood platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

25 September 2017

Identification of a receptor for ADP on blood platelets by photoaffinity labelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

15 June 2018

Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

15 June 2018

The role of protein sulfhydryl groups and protein disulfides of the platelet surface in aggregation processes involving thiol exchange reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

Platelet reactivity and clopidogrel resistance are associated with the H2 haplotype of the P2Y12-ADP receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

Synthesis and preliminary evaluation of [3H]PSB-0413, a selective antagonist radioligand for platelet P2Y12 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

P2Y1 gene polymorphism and ADP-induced platelet response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

Preparation of washed platelet suspensions from human and rodent blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

P2Y12 H2 haplotype is associated with peripheral arterial disease: a case-control study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

Platelets from a patient heterozygous for the defect of P2CYC receptors for ADP have a secretion defect despite normal thromboxane A2 production and normal granule stores: further evidence that some cases of platelet 'primary secretion defect' are h

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

Purinoceptors on blood platelets: further pharmacological and clinical evidence to suggest the presence of two ADP receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568427

21 August 2018

Isolation and Characterization of Plasma Membranes from Human Blood Platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bleeding manifestations of congenital and drug-induced defects of the platelet P2Y12 receptor for adenosine diphosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of adenosine diphosphate to human blood platelets and to isolated blood platelet membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homogenization by nitrogen cavitation technique applied to platelet subcellular fractionation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of [3H]-2-methylthio ADP to rat platelets--effect of clopidogrel and ticlopidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P2 receptors, platelet function and pharmacological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

β-arrestin-1 participates in thrombosis and regulates integrin aIIbβ3 signalling without affecting P2Y receptors desensitisation and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of high-affinity (Kd 0.35 mumol/L) and low-affinity (Kd 7.9 mumol/L) platelet binding sites for ADP and competition by ADP analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desensitization of the platelet aggregation response to ADP: differential down-regulation of the P2Y1 and P2cyc receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of methyl mercury on platelets: induction of aggregation and release via activation of the prostaglandin synthesis pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Methylthioadenosine [beta-32P]diphosphate: synthesis and use as probe of platelet ADP receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22892887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11302-012-9329-0

1 reference

Europe PubMed Central

10 September 2017

1 reference

Europe PubMed Central

10 September 2017

1 reference

Europe PubMed Central

10 September 2017

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