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Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection.
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1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
title
Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author
Emanuele Buratti
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
S Eréndira Avendaño-Vázquez
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Ashish Dhir
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Nicholas Jarvis Proudfoot
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author name string
Sara Bembich
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Francisco E Baralle
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
language of work or name
English
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publication date
1 August 2012
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
published in
Genes & Development
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
volume
26
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
issue
15
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
page(s)
1679-1684
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
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RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage
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PubMed Central
reference URL
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Ending the message: poly(A) signals then and now
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11 September 2017
TDP-43: new aspects of autoregulation mechanisms in RNA binding proteins and their connection with human disease
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PubMed Central
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Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.
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reference URL
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TDP-43 regulates its mRNA levels through a negative feedback loop
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TDP-43-based animal models of neurodegeneration: new insights into ALS pathology and pathophysiology
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Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy
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U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation
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Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice
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A Drosophila model for TDP-43 proteinopathy
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11 September 2017
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
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Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis
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Polyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing
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Pre-mRNA processing reaches back to transcription and ahead to translation
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Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression
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Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration
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Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9
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11 September 2017
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
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14 September 2017
TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia
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15 June 2018
Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements
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21 August 2018
Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II
1 reference
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PubMed
reference URL
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retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1101/GAD.194829.112
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PMCID
3418585
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PubMed ID
22855830
1 reference
stated in
Europe PubMed Central
PMCID
3418585
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22855830%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
ResearchGate publication ID
230600071
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