(Q39314503)

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c-Kit mediates chemoresistance and tumor-initiating capacity of ovarian cancer cells through activation of Wnt/β-catenin-ATP-binding cassette G2 signaling.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22797058%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

c-Kit mediates chemoresistance and tumor-initiating capacity of ovarian cancer cells through activation of Wnt/β-catenin-ATP-binding cassette G2 signaling (English)

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7 February 2020

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7 February 2020

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W K Chau

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7 February 2020

A S C Mak

3

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7 February 2020

H-C Lai

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7 February 2020

A S T Wong

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7 February 2020

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16 July 2012

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7 February 2020

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7 February 2020

32

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7 February 2020

22

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7 February 2020

2767-2781

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7 February 2020

https://scigraph.springernature.com/pub.10.1038/onc.2012.290

0 references

Cancer statistics, 2010

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

The biology of ovarian cancer: new opportunities for translation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Identification and characterization of ovarian cancer-initiating cells from primary human tumors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Stem cells, cancer, and cancer stem cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Ovarian surface epithelium: biology, endocrinology, and pathology

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Expression of c-ABL, c-KIT, and platelet-derived growth factor receptor-beta in ovarian serous carcinoma and normal ovarian surface epithelium

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

c-KIT expression and correlation with chemotherapy resistance in ovarian carcinoma: an immunocytochemical study

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Immunohistochemical detection of human telomerase reverse transcriptase (hTERT) and c-kit in serous ovarian carcinoma: a clinicopathologic study

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Phase II trial of imatinib mesylate in recurrent, biomarker positive, ovarian cancer (Southwest Oncology Group Protocol S0211).

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Phase II evaluation of imatinib mesylate in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group Study

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Tumour stem cells and drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Wnt/beta-catenin signaling in cancer stemness and malignant behavior

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

A Wnt survival guide: from flies to human disease.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Prolonged beta-catenin stabilization and tcf-dependent transcriptional activation in hyperplastic cutaneous wounds

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Phase II trial of imatinib mesylate in patients with recurrent platinum- and taxane-resistant epithelial ovarian and primary peritoneal cancers.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Imatinib mesylate in combination with docetaxel for the treatment of patients with advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis : a Hoosier Oncology Group trial.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

The development of imatinib as a therapeutic agent for chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Novel treatment of ovarian cancer cell lines with Imatinib mesylate combined with Paclitaxel and Carboplatin leads to receptor-mediated antiproliferative effects

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Multicellular spheroids in ovarian cancer metastases: Biology and pathology.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Ovarian cancer cells with the CD117 phenotype are highly tumorigenic and are related to chemotherapy outcome

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Targeting c-Kit mutations: basic science to novel therapies

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Hypoxia-inducible factor 1 alpha (HIF-1 alpha) gene expression in human ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Transcriptional regulation of ABC drug transporters

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

beta-catenin expression, DNA ploidy and clinicopathological features in ovarian cancer: a study in 253 patients.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Stem cell pathways contribute to clinical chemoresistance in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Treatment-related protein biomarker expression differs between primary and recurrent ovarian carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Is cancer a disease of self-seeding?

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

21 January 2018

Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

31 March 2020

AKT mediates the pro-survival effects of KIT in ovarian cancer cells and is a determinant of sensitivity to imatinib mesylate

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

31 March 2020

Gonadotropin-induced apoptosis in human ovarian surface epithelial cells is associated with cyclooxygenase-2 up-regulation via the beta-catenin/T-cell factor signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

31 March 2020

A prospective analysis of imatinib-induced c-kit modulation in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

31 March 2020

beta-catenin nuclear localization is associated with grade in ovarian serous carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

31 March 2020

Resistance to c-KIT kinase inhibitors conferred by V654A mutation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.290

31 March 2020

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