(Q39322543)

English

Diacylglycerol acyltransferase 2 acts upstream of diacylglycerol acyltransferase 1 and utilizes nascent diglycerides and de novo synthesized fatty acids in HepG2 cells

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scholarly article

1 reference

Europe PubMed Central

11 September 2017

Diacylglycerol acyltransferase 2 acts upstream of diacylglycerol acyltransferase 1 and utilizes nascent diglycerides and de novo synthesized fatty acids in HepG2 cells (English)

1 reference

Europe PubMed Central

11 September 2017

0 references

author name string

Haja R Wurie

1

1 reference

Europe PubMed Central

11 September 2017

Linda Buckett

2

1 reference

Europe PubMed Central

11 September 2017

Victor A Zammit

3

1 reference

Europe PubMed Central

11 September 2017

language of work or name

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publication date

31 July 2012

1 reference

Europe PubMed Central

11 September 2017

1 reference

Europe PubMed Central

11 September 2017

279

1 reference

Europe PubMed Central

11 September 2017

17

1 reference

Europe PubMed Central

11 September 2017

3033-3047

1 reference

Europe PubMed Central

11 September 2017

Enzymes of triacylglycerol synthesis and their regulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Lipopenia and skin barrier abnormalities in DGAT2-deficient mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

DGAT2 is a new diacylglycerol acyltransferase gene family: purification, cloning, and expression in insect cells of two polypeptides from Mortierella ramanniana with diacylglycerol acyltransferase activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Tung tree DGAT1 and DGAT2 have nonredundant functions in triacylglycerol biosynthesis and are localized to different subdomains of the endoplasmic reticulum.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Hydrophobic-domain-dependent protein-protein interactions mediate the localization of GPAT enzymes to ER subdomains

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Colocalization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Regulation of Triglyceride Metabolism. II. Function of mitochondrial GPAT1 in the regulation of triacylglycerol biosynthesis and insulin action

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Mitochondrial glycerol phosphate acyltransferase directs the incorporation of exogenous fatty acids into triacylglycerol

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Subcellular localization of B apoprotein of plasma lipoproteins in rat liver

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Overt and latent activities of diacylglycerol acytransferase in rat liver microsomes: possible roles in very-low-density lipoprotein triacylglycerol secretion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Diacylglycerol acyltransferases: Potential roles as pharmacological targets

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Differential effects of fenofibrate or simvastatin treatment of rats on hepatic microsomal overt and latent diacylglycerol acyltransferase activities

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Evidence that diacylglycerol acyltransferase 1 (DGAT1) has dual membrane topology in the endoplasmic reticulum of HepG2 cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Increased very low density lipoprotein secretion and gonadal fat mass in mice overexpressing liver DGAT1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Membrane topology and identification of key functional amino acid residues of murine acyl-CoA:diacylglycerol acyltransferase-2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Role of insulin in hepatic fatty acid partitioning: emerging concepts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Biochemical and physiological function of stearoyl-CoA desaturase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Subcellullar localization, developmental expression and characterization of a liver triacylglycerol hydrolase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Novel acyl-coenzyme A:monoacylglycerol acyltransferase plays an important role in hepatic triacylglycerol secretion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Contributions of de novo synthesis of fatty acids to total VLDL-triglyceride secretion during prolonged hyperglycemia/hyperinsulinemia in normal man.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Regulation of hepatic de novo lipogenesis in humans

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Altered lipid droplet dynamics in hepatocytes lacking triacylglycerol hydrolase expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Role of endoplasmic reticulum neutral lipid hydrolases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

The assembly and secretion of apolipoprotein B-containing lipoproteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Genetic control of de novo lipogenesis: role in diet-induced obesity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

Rapid transbilayer diffusion of 1,2-diacylglycerol and its relevance to control of membrane curvature

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08684.X

21 January 2018

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10.1111/J.1742-4658.2012.08684.X

1 reference

Europe PubMed Central

11 September 2017

1 reference

Europe PubMed Central

11 September 2017

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