(Q39343138)

11 September 2017

title

A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo (English)

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11 September 2017

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C Magkoufopoulou

1

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11 September 2017

S M H Claessen

2

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11 September 2017

M Tsamou

3

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11 September 2017

D G J Jennen

4

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11 September 2017

J C S Kleinjans

5

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11 September 2017

J H M van Delft

6

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11 September 2017

language of work or name

English

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publication date

23 May 2012

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11 September 2017

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11 September 2017

volume

33

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11 September 2017

issue

7

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11 September 2017

page(s)

1421-1429

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11 September 2017

cites work

Cancer statistics, 2010

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Hereditary breast and ovarian cancer due to mutations in BRCA1 and BRCA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Environmental and occupational causes of cancer: new evidence 2005-2007

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Inherited susceptibility to common cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

The molecular biology of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Guidelines for the welfare and use of animals in cancer research

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Differentiation of DNA reactive and non-reactive genotoxic mechanisms using gene expression profile analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Genistein induction of human sulfotransferases in HepG2 and Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Trovafloxacin-induced gene expression changes in liver-derived in vitro systems: comparison of primary human hepatocytes to HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Biotransformation pathway maps in WikiPathways enable direct visualization of drug metabolism related expression changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Use of four new human-derived liver-cell lines for the detection of genotoxic compounds in the single-cell gel electrophoresis (SCGE) assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Evaluation of high-throughput genotoxicity assays used in profiling the US EPA ToxCast chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

NuGO contributions to GenePattern.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Diagnosis of multiple cancer types by shrunken centroids of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

DAVID: Database for Annotation, Visualization, and Integrated Discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Genotoxicity studies of three triazine herbicides: in vivo studies using the alkaline single cell gel (SCG) assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Azathioprine, a genotoxic agent to be considered non-genotoxic in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Series: current issues in mutagenesis and carcinogenesis, No. 65. The genotoxicity and carcinogenicity of paracetamol: a regulatory (re)view

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

An in vivo comet assay of multiple organs (liver, kidney and bone marrow) in mice treated with methyl methanesulfonate and acetaminophen accompanied by hematology and/or blood chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Expression of specific hepatocyte and cholangiocyte transcription factors in human liver disease and embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Regulation of hepatocyte nuclear factor 4 alpha-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

Epigenetic inhibition of nuclear receptor small heterodimer partner is associated with and regulates hepatocellular carcinoma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS182

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGS182

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11 September 2017

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