(Q39348417)

English

An inhibitor of transforming growth factor beta type I receptor ameliorates muscle atrophy in a mouse model of caveolin 3-deficient muscular dystrophy

scientific article published on 14 May 2012

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scholarly article

1 reference

Europe PubMed Central

11 September 2017

An inhibitor of transforming growth factor beta type I receptor ameliorates muscle atrophy in a mouse model of caveolin 3-deficient muscular dystrophy (English)

1 reference

Europe PubMed Central

11 September 2017

author name string

Yutaka Ohsawa

1

1 reference

Europe PubMed Central

11 September 2017

Tadashi Okada

2

1 reference

Europe PubMed Central

11 September 2017

Shin-Ichiro Nishimatsu

3

1 reference

Europe PubMed Central

11 September 2017

Masatoshi Ishizaki

4

1 reference

Europe PubMed Central

11 September 2017

Tomohiro Suga

5

1 reference

Europe PubMed Central

11 September 2017

Masahiro Fujino

6

1 reference

Europe PubMed Central

11 September 2017

Tatsufumi Murakami

7

1 reference

Europe PubMed Central

11 September 2017

Makoto Uchino

8

1 reference

Europe PubMed Central

11 September 2017

Kunihiro Tsuchida

9

1 reference

Europe PubMed Central

11 September 2017

Sumihare Noji

10

1 reference

Europe PubMed Central

11 September 2017

Atsushi Hinohara

11

1 reference

Europe PubMed Central

11 September 2017

Toshiyuki Shimizu

12

1 reference

Europe PubMed Central

11 September 2017

Kiyoshi Shimizu

13

1 reference

Europe PubMed Central

11 September 2017

Yoshihide Sunada

14

1 reference

Europe PubMed Central

11 September 2017

publication date

14 May 2012

1 reference

Europe PubMed Central

11 September 2017

Laboratory Investigation

1 reference

Europe PubMed Central

11 September 2017

92

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Europe PubMed Central

11 September 2017

8

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Europe PubMed Central

11 September 2017

1100-1114

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Europe PubMed Central

11 September 2017

https://scigraph.springernature.com/pub.10.1038/labinvest.2012.78

0 references

Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Reversing cachexia.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Signaling pathways perturbing muscle mass

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Molecular treatments in Duchenne muscular dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Muscular atrophy of caveolin-3-deficient mice is rescued by myostatin inhibition

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Induction of cachexia in mice by systemically administered myostatin.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Caveolinopathies: from the biology of caveolin-3 to human diseases

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Transgenic mice expressing mutant caveolin-3 show severe myopathy associated with increased nNOS activity

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Development of TGF-beta signalling inhibitors for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

TGF-beta signaling in tumor suppression and cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5).

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Visualization of dystrophic muscle fibers in mdx mouse by vital staining with Evans blue: evidence of apoptosis in dystrophin-deficient muscle.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Full functional rescue of a complete muscle (TA) in dystrophic hamsters by adeno-associated virus vector-directed gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Myostatin is an inhibitor of myogenic differentiation.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Point mutated caveolin-3 form (P104L) impairs myoblast differentiation via Akt and p38 signalling reduction, leading to an immature cell signature

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Regulation and function of skeletal muscle stem cells

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

A small molecule-kinase interaction map for clinical kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Regulation of myogenic differentiation by type beta transforming growth factor

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Type beta transforming growth factor is an inhibitor of myogenic differentiation

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Regulation of muscle mass by follistatin and activins

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Expression of transforming growth factor-beta 1 in dystrophic patient muscles correlates with fibrosis. Pathogenetic role of a fibrogenic cytokine.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Myostatin negatively regulates satellite cell activation and self-renewal

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Lack of myostatin results in excessive muscle growth but impaired force generation

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Efficacy of systemic morpholino exon-skipping in Duchenne dystrophy dogs

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

21 January 2018

Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

7 January 2021

based on heuristic

inferred from DOI database lookup

Culturing satellite cells from living single muscle fiber explants

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted down-regulation of caveolin-3 is sufficient to inhibit myotube formation in differentiating C2C12 myoblasts. Transient activation of p38 mitogen-activated protein kinase is required for induction of caveolin-3 expression and subsequent myot

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

7 January 2021

based on heuristic

inferred from DOI database lookup

The modulation of caveolin-1 expression controls satellite cell activation during muscle repair

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.78

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/LABINVEST.2012.78

1 reference

Europe PubMed Central

11 September 2017

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release_n4bz77oqefafbf27phzebr2sme

1 reference

https://api.fatcat.wiki/v0/release/n4bz77oqefafbf27phzebr2sme

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

11 September 2017

ResearchGate publication ID

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