(Q39354035)

11 September 2017

title

EphB4 promotes or suppresses Ras/MEK/ERK pathway in a context-dependent manner: Implications for EphB4 as a cancer target (English)

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11 September 2017

Zhan Xiao

1

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11 September 2017

Rosa Carrasco

2

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11 September 2017

Krista Kinneer

3

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11 September 2017

Darrin Sabol

4

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11 September 2017

Bahija Jallal

5

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11 September 2017

Steve Coats

6

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11 September 2017

David A Tice

7

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11 September 2017

publication date

1 June 2012

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Cancer Biology and Therapy

11 September 2017

published in

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11 September 2017

volume

13

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11 September 2017

issue

8

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11 September 2017

page(s)

630-637

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Eph-ephrin bidirectional signaling in physiology and disease

11 September 2017

cites work

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Bidirectional Eph-ephrin signaling during axon guidance

21 January 2018

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Cell-cell signaling via Eph receptors and ephrins

21 January 2018

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Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development

21 January 2018

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Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells

21 January 2018

1 reference

Eph receptors and ephrins in cancer: bidirectional signalling and beyond

21 January 2018

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The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

21 January 2018

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Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia

21 January 2018

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EphB/EphrinB receptors and Wnt signaling in colorectal cancer

21 January 2018

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EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.

21 January 2018

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EPHB4 and survival of colorectal cancer patients.

21 January 2018

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EphB receptor activity suppresses colorectal cancer progression

21 January 2018

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The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome

21 January 2018

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Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression

21 January 2018

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EphB4 expression and biological significance in prostate cancer

21 January 2018

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Inhibition of tumor growth and angiogenesis by soluble EphB4.

21 January 2018

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The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth

21 January 2018

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Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction

21 January 2018

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EphrinA1 repulsive response is regulated by an EphA2 tyrosine phosphatase

21 January 2018

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Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

21 January 2018

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Paradoxes of the EphB4 receptor in cancer

21 January 2018

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Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

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Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt

21 January 2018

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Src kinase up-regulates the ERK cascade through inactivation of protein phosphatase 2A following cerebral ischemia

21 January 2018

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Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes

21 January 2018

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Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites

21 January 2018

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Receptor tyrosine kinase EphB4 is a survival factor in breast cancer

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4161/CBT.20080

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11 September 2017

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