(Q39374641)

11 September 2017

title

Tryptophan: the key to boosting brain serotonin synthesis in depressive illness (English)

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11 September 2017

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Abdulla A-B Badawy

1

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11 September 2017

language of work or name

English

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publication date

31 July 2013

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Journal of Psychopharmacology

11 September 2017

published in

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11 September 2017

volume

27

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11 September 2017

issue

10

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11 September 2017

page(s)

878-893

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Correlation of kynurenine excretion with liver tryptophan pyrrolase levels in disease and after hydrocortisone induction

11 September 2017

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Serotonin and drug-induced therapeutic responses in major depression, obsessive-compulsive and panic disorders

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Cytokine modulation by glucocorticoids: mechanisms and actions in cellular studies

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Tryptophan availability selectively limits NO-synthase induction in macrophages.

21 January 2018

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Tryptophan-nicotinamide, imipramine and their combination in depression. A controlled study

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21 January 2018

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Tryptophan Pyrrolase—A Biochemical Factor in Depressive Illness?

21 January 2018

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Effects on plasma and brain tryptophan in the rat of drugs and hormones that influence the concentration of unesterified fatty acid in the plasma

21 January 2018

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Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control study.

21 January 2018

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Combined use of SSRIs and NSAIDs increases the risk of gastrointestinal adverse effects

21 January 2018

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Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan.

21 January 2018

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A meta-analysis of cytokines in major depression

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Decrease of 5-hydroxytryptamine in the brain provoked by hydrocortisone and its prevention by allopurinol.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide.

21 January 2018

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Appearance of new hepatic glucocorticoid binding proteins under various stressful conditions: relation to endogenous glucocorticoid secretion.

21 January 2018

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The nature of dopamine dysfunction in schizophrenia and what this means for treatment

21 January 2018

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Nitric oxide-mediated regulation of gamma interferon-induced bacteriostasis: inhibition and degradation of human indoleamine 2,3-dioxygenase

21 January 2018

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Glucocorticoid receptor antagonists hasten and augment neurochemical responses to a selective serotonin reuptake inhibitor antidepressant

21 January 2018

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The metabolism of a tryptophan load in rat brain and liver. The influence of hydrocortisone and allopurinol

21 January 2018

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The benefit of oestrogens and progestogens in postnatal depression

21 January 2018

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Oestrogen: an overlooked mediator in the neuropsychopharmacology of treatment response?

21 January 2018

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Is aspirin, as used for antithrombosis, an emotion-modulating agent?

21 January 2018

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Serumconcentrations of non esterified fatty acids during operative stress and blockade of betaadrenergic receptors (author's transl)

21 January 2018

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Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect

21 January 2018

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24-hour profiles of adrenocorticotropin, cortisol, and growth hormone in major depressive illness: effect of antidepressant treatment.

21 January 2018

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Plasma tryptophan to large neutral amino acids ratio and therapeutic response to a selective serotonin uptake inhibitor

21 January 2018

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Predictive value of tryptophan/large neutral amino acids ratio to antidepressant response.

21 January 2018

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Efficacy and tolerability of selective serotonin reuptake inhibitors compared with tricyclic antidepressants in depression treated in primary care: systematic review and meta-analysis

21 January 2018

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The Timing of Antidepressant Effects: A Comparison of Diverse Pharmacological and Somatic Treatments.

21 January 2018

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Effects of dexamethasone on the availability of L-tryptophan and on the insulin and FFA concentrations in unipolar depressed patients.

21 January 2018

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Increased neopterin and interferon-gamma secretion and lower availability of L-tryptophan in major depression: further evidence for an immune response

21 January 2018

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The decreased availability of L-tryptophan in depressed females: clinical and biological correlates

21 January 2018

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Stimulation of liver tryptophan pyrrolase during heat exposure

21 January 2018

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Serum concentrations of 2',5'-oligoadenylate synthetase, neopterin, and beta-glucan in patients with chronic fatigue syndrome and in patients with major depression

21 January 2018

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Predictive value of amino acids in the treatment of major depression with fluvoxamine

21 January 2018

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Different properties of the central and peripheral forms of human tryptophan hydroxylase

21 January 2018

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21 January 2018

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Serotonergic function in the affective disorders: the effect of antidepressants and lithium on the 5-hydroxytryptophan-induced increase in serum cortisol

21 January 2018

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Fluoxetine, but not tricyclic antidepressants, potentiates the 5-hydroxytryptophan-mediated increase in plasma cortisol and prolactin secretion in subjects with major depression or with obsessive compulsive disorder.

21 January 2018

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Shortened onset of action of antidepressants in major depression using acetylsalicylic acid augmentation: a pilot open-label study

21 January 2018

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Differential response of plasma glucose, amino acids and nonesterified fatty acids to insulin in depressed patients.

21 January 2018

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Tianeptine, a selective enhancer of serotonin uptake in rat brain

21 January 2018

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A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression

21 January 2018

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L-5HTP in depression resistant to re-uptake inhibitors. An open comparative study with tranylcypromine.

21 January 2018

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Plasma neopterin in major depression: relationship to basal and stimulated pituitary-adrenal cortical axis function

21 January 2018

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Do antidepressants regulate how cortisol affects the brain?

21 January 2018

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Corticosteroid receptor mediated effects on mood in humans

21 January 2018

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Platelet serotonin and plasma tryptophan decreases in endogenous depression. Clinical, therapeutic, and biological correlations

21 January 2018

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Plasma tryptophan to large neutral amino acid ratios in depressed and normal subjects

21 January 2018

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https://api.crossref.org/works/10.1177%2F0269881113499209

Antidepressant treatment with mirtazapine, but not venlafaxine, lowers cortisol concentrations in saliva: a randomised open trial

21 January 2018

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Aspirin down-regulates tryptophan degradation in stimulated human peripheral blood mononuclear cells in vitro

21 January 2018

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Neuroendocrinological mechanisms of actions of antidepressant drugs

21 January 2018

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Enhancement of the Antidepressant Response to <i>L</i>-Tryptophan by a Liver Pyrrolase Inhibitor: a Rational Treatment Approach

21 January 2018

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Both acute and subchronic treatments with pindolol, a 5-HT(1A) and β₁ and β₂ adrenoceptor antagonist, elevate regional serotonin synthesis in the rat brain: an autoradiographic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113499209

Plasma pterins and folate in late life depression: The Rotterdam Study

21 January 2018

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https://api.crossref.org/works/10.1177%2F0269881113499209

Boosting serotonin in the brain: is it time to revamp the treatment of depression?

21 January 2018

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https://api.crossref.org/works/10.1177%2F0269881113499209

Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan

21 January 2018

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https://api.crossref.org/works/10.1177%2F0269881113499209

Early and delayed onset of response to antidepressants in individual trajectories of change during treatment of major depression: a secondary analysis of data from the Genome-Based Therapeutic Drugs for Depression (GENDEP) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113499209

Immune Activation and Neuropsychiatric Symptoms in HIV Infection

21 January 2018

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https://api.crossref.org/works/10.1177%2F0269881113499209

Effects of antidepressants on the brain/plasma distribution of corticosterone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113499209

Modulation of neopterin formation and tryptophan degradation by Th1- and Th2-derived cytokines in human monocytic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113499209

Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113499209

Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding.

21 January 2018

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Treatment of depression with antiglucocorticoid drugs

21 January 2018

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https://api.crossref.org/works/10.1177%2F0269881113499209

Human indolylamine 2,3-dioxygenase. Its tissue distribution, and characterization of the placental enzyme

21 January 2018

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https://api.crossref.org/works/10.1177%2F0269881113499209

Induction of pulmonary indoleamine 2,3-dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide

21 January 2018

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https://api.crossref.org/works/10.1177%2F0269881113499209

Mechanism of decline in rat brain 5-hydroxytryptamine after induction of liver tryptophan pyrrolase by hydrocortisone: roles of tryptophan catabolism and kynurenine synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113499209

L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113499209

21 January 2018

Identifiers

DOI

10.1177/0269881113499209

1 reference

11 September 2017

1 reference