(Q39376172)

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Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway

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Europe PubMed Central

PubMed publication ID

11 September 2017

Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway (English)

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Europe PubMed Central

PubMed publication ID

11 September 2017

3-aminopropanenitrile

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ChEBI release 2020-05-28

author name string

Li-Ching Chen

1

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Europe PubMed Central

PubMed publication ID

11 September 2017

Shih-Hsin Tu

2

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11 September 2017

Ching-Shui Huang

3

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11 September 2017

Ching-Shyang Chen

4

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11 September 2017

Chi-Tang Ho

5

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11 September 2017

Hsiao-Wei Lin

6

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11 September 2017

Chia-Hwa Lee

7

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11 September 2017

Hui-Wen Chang

8

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11 September 2017

Chien-Hsi Chang

9

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11 September 2017

Chih-Hsiung Wu

10

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11 September 2017

Wen-Sen Lee

11

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11 September 2017

Yuan-Soon Ho

12

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11 September 2017

language of work or name

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publication date

21 March 2012

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11 September 2017

Breast Cancer Research and Treatment

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11 September 2017

134

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11 September 2017

3

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11 September 2017

989-1004

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Europe PubMed Central

PubMed publication ID

11 September 2017

https://scigraph.springernature.com/pub.10.1007/s10549-012-1986-8

0 references

Increasingly strong reduction in breast cancer mortality due to screening

1 reference

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21 January 2018

First-line chemotherapy with or without biologic agents for metastatic breast cancer.

1 reference

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21 January 2018

The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival

1 reference

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21 January 2018

Association of an extracellular matrix gene cluster with breast cancer prognosis and endocrine therapy response

1 reference

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21 January 2018

Differential expression of lysyl oxidases LOXL1 and LOX during growth and aging suggests specific roles in elastin and collagen fiber remodeling in rat aorta

1 reference

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21 January 2018

Matrix crosslinking forces tumor progression by enhancing integrin signaling

1 reference

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21 January 2018

Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis

1 reference

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21 January 2018

Lysyl oxidase: properties, regulation and multiple functions in biology

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Molecular cloning of human lysyl oxidase and assignment of the gene to chromosome 5q23.3-31.2

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Active lysyl oxidase (LOX) correlates with focal adhesion kinase (FAK)/paxillin activation and migration in invasive astrocytes

1 reference

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21 January 2018

Lysyl oxidase: a potential target for cancer therapy

1 reference

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21 January 2018

Magnolol induces apoptosis via activation of both mitochondrial and death receptor pathways in A375-S2 cells

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Anticancer potential of magnolol for lung cancer treatment

1 reference

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21 January 2018

Magnolol down-regulates HER2 gene expression, leading to inhibition of HER2-mediated metastatic potential in ovarian cancer cells

1 reference

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21 January 2018

Inhibitory effect of magnolol on TPA-induced skin inflammation and tumor promotion in mice

1 reference

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21 January 2018

The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Magnolol inhibits human glioblastoma cell proliferation through upregulation of p21/Cip1.

1 reference

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21 January 2018

Induction of apoptosis by hydroxydibenzoylmethane through coordinative modulation of cyclin D3, Bcl-X(L), and Bax, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Increased expression of enolase alpha in human breast cancer confers tamoxifen resistance in human breast cancer cells

1 reference

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21 January 2018

Overexpression and activation of the alpha9-nicotinic receptor during tumorigenesis in human breast epithelial cells.

1 reference

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Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopes

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Nicotine promotes cell migration through alpha7 nicotinic acetylcholine receptor in gastric cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Romidepsin (FK228), a potent histone deacetylase inhibitor, induces apoptosis through the generation of hydrogen peroxide.

1 reference

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Combination treatment with luteolin and quercetin enhances antiproliferative effects in nicotine-treated MDA-MB-231 cells by down-regulating nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Disruption of focal adhesion kinase slows transendothelial migration of AU-565 breast cancer cells

1 reference

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21 January 2018

Invading basement membrane matrix is sufficient for MDA-MB-231 breast cancer cells to develop a stable in vivo metastatic phenotype

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Three-dimensional collagen represses cyclin E1 via β1 integrin in invasive breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Focal adhesion kinase signaling at sites of integrin-mediated adhesion controls axon pathfinding.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Reactive oxygen species signaling through regulation of protein tyrosine phosphorylation in endothelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

A highly bone marrow metastatic murine breast cancer model established through in vivo selection exhibits enhanced anchorage-independent growth and cell migration mediated by ICAM-1.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Increased lysyl oxidase activity in aortas of hypertensive rats and effect of β-aminopropionitrile

1 reference

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21 January 2018

Fully processed lysyl oxidase catalyst translocates from the extracellular space into nuclei of aortic smooth-muscle cells

1 reference

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Hydrogen peroxide activates focal adhesion kinase and c-Src by a phosphatidylinositol 3 kinase-dependent mechanism and promotes cell migration in Caco-2 cell monolayers

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

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Demonstration of in vitro interaction between tumor suppressor lysyl oxidase and histones H1 and H2: definition of the regions involved

1 reference

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Chromatin supraorganization, mitotic abnormalities and proliferation in cells with increased or down-regulated lox expression: Indirect evidence of a LOX-histone H1 interaction in vivo

1 reference

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21 January 2018

Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Cyclooxygenase-2 inhibition: effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer

1 reference

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Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells

1 reference

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Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer

1 reference

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The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

1 reference

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21 January 2018

Quercetin-induced ubiquitination and down-regulation of Her-2/neu

1 reference

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21 January 2018

Magnolol suppresses metastasis via inhibition of invasion, migration, and matrix metalloproteinase-2/-9 activities in PC-3 human prostate carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Inhibitory effect of magnolol on tumour metastasis in mice

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

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Lysyl oxidase 473 G>A polymorphism and breast cancer susceptibility in Chinese Han population.

1 reference

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Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Lysyl Oxidase Activates the Transcription Activity of Human Collagene III Promoter

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-1986-8

21 January 2018

Identifiers

10.1007/S10549-012-1986-8

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

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